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SNAIL 抗体 (N-Term)
SNAI1
适用: 人, 小鼠, 大鼠
WB, IHC (p), EIA
宿主: 山羊
Polyclonal
unconjugated
SNAIL抗体详情
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抗原
See all SNAIL (SNAI1) 抗体
SNAIL (SNAI1)
抗原表位
All epitopes for SNAIL 抗体
N-Term
适用
All reactivities for SNAIL 抗体
人, 小鼠, 大鼠
宿主
All hosts for SNAIL 抗体
山羊
克隆类型
All clonalities for SNAIL 抗体
多克隆
标记
All conjugates for SNAIL 抗体
This SNAIL antibody is un-conjugated
应用范围
All applications for SNAIL 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
序列
RKPSDPNRKP NY-C
特异性
Snail homolog 1 / SNAI1
交叉反应 (详细)
Species reactivity (expected):Rat. Species reactivity (tested):Human, Mouse.
纯化方法
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
免疫原
Peptide with sequence from the N Terminus of the protein sequence according to NP_005976.2. Genename: SNAI1
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Discover our top product SNAI1 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
SNAIL目标详情
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抗原
SNAIL (SNAI1)
别名
SNAI1 (SNAI1 产品 )
别名
SLUGH2 antibody, SNA antibody, SNAH antibody, SNAIL antibody, SNAIL1 antibody, dJ710H13.1 antibody, AI194338 antibody, Sna antibody, Sna1 antibody, Snail antibody, Snail1 antibody, SNAI1 antibody, BG:DS01845.1 antibody, CG3956 antibody, Dmel\\CG3956 antibody, Sco antibody, br28 antibody, br29 antibody, l(2)35Db antibody, l(2)br28 antibody, l(2)br29 antibody, l(3)br28 antibody, l35Db antibody, sn antibody, Xsnail antibody, sna antibody, snail1 antibody, xSna antibody, Snai antibody, sna2 antibody, snail2 antibody, cb643 antibody, sna-1 antibody, sna1 antibody, snai1 antibody, snail1a antibody, zgc:109820 antibody, snail family transcriptional repressor 1 antibody, snail family zinc finger 1 antibody, snail homolog 1 (Drosophila) antibody, snail antibody, zinc-finger transcription factor Snail antibody, snail family zinc finger 1 S homeolog antibody, protein escargot antibody, transcription factor protein antibody, snail zinc finger protein antibody, snail family zinc finger 1b antibody, snail family zinc finger 1a antibody, SNAI1 antibody, Snai1 antibody, sna antibody, snail antibody, snai1.S antibody, LOC410464 antibody, snai1b antibody, snai1a antibody
背景
Zinc finger protein SNAI1 (SNAIL) is a zinc finger transcriptional repressor which down regulates the expression of ectodermal gene within the mesoderm and thus functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stroma may be a new putative prognosis marker for colon tumors. In recent studies SNAI1 is found to be potential target for proteasome degradation by hypoxia-controlled FBXL14 ubiquitin ligase targets.Synonyms: Protein snail homolog 1, SNAH, Zinc finger protein SNAI1
基因ID
6615
NCBI登录号
NP_005976
UniProt
O95863
途径
Negative Regulation of intrinsic apoptotic Signaling
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