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小鼠 anti-人 IgA (Free & Bound), (Secretory Component) Antibody (FITC)

WB, IF, IHC (fro), IP, EIA Monoclonal NI 194-4 (A89-039) IgG1 FITC
产品编号 ABIN567757
发货至: 中国
  • 抗原 See all IgA products
    IgA
    抗原表位
    • 105
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    • 38
    • 15
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    Free & Bound, Secretory Component
    适用
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    宿主
    • 201
    • 98
    • 46
    • 17
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    • 2
    小鼠
    克隆类型
    • 308
    • 59
    单克隆
    标记
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    FITC
    应用范围
    • 179
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    产品特性
    Molar Ratio: Fluorochrome/IgG: aprox. 2.0
    免疫原
    Highly purified Secretory component isolated from Human milk.
    克隆位点
    NI 194-4 (A89-039)
    亚型
    IgG1
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Absorption / Emission: 492 nm / 515 nm

    限制
    仅限研究用
  • 溶解方式
    Restore by adding 0.5 mL sterile distilled water.
    浓度
    0.4 mg/mL
    缓冲液
    PBS, pH 7.2 without preservatives and foreign proteins.
    储存液
    Without preservative
    注意事项
    Product is photosensitive and should be protected from light.
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one week or (in aliquots) at -28 °C for longer.
  • 抗原
    IgA
    Abstract
    IgA 产品
    物质类
    Antibody
    背景
    Secretory Component Glycoprotein is an epithelial transport receptor for polymeric IgA and IgM. Antibody to secretory component has been shown to be useful for identifying glandular carcinomas. Defects in Secretory Component Glycoprotein are the cause of lipoid proteinosis (LiP), also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane. Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland.Synonyms: Human Immunoglobulin A
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