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SQSTM1 抗体 (AA 1-440)

SQSTM1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C11 unconjugated
产品编号 ABIN563860
发货至: 中国
  • 抗原 See all SQSTM1 抗体
    SQSTM1 (Sequestosome 1 (SQSTM1))
    抗原表位
    • 19
    • 17
    • 15
    • 13
    • 11
    • 11
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
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    • 5
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-440
    适用
    • 171
    • 64
    • 61
    • 18
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 146
    • 23
    • 1
    • 1
    小鼠
    克隆类型
    • 145
    • 26
    单克隆
    标记
    • 77
    • 13
    • 12
    • 8
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SQSTM1 antibody is un-conjugated
    应用范围
    • 121
    • 57
    • 49
    • 40
    • 25
    • 23
    • 18
    • 16
    • 14
    • 13
    • 10
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    原理
    Mouse monoclonal antibody raised against a full length recombinant SQSTM1.
    序列
    MASLTVKAYL LGKEDAAREI RRFSFCCSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN MVHPNVICDG CNGPVVGTRY KCSVCPDYDL CSVCEGKGLH RGHTKLAFPS PFGHLSEGFS HSRWLRKVKH GHFGWPGWEM GPPGNWSPRP PRAGEARPGP TAESASGPSE DPSVNFLKNV GESVAAALSP LGIEVDIDVE HGGKRSRLTP VSPESSSTEE KSSSQPSSCC SDPSKPGGNV EGATQSLAEQ MRKIALESEG RPEEQMESDN CSGGDDDWTH LSSKEVDPST GELQSLQMPE SEGPSSLDPS QEGPTGLKEA ALYPHLPPEA DPRLIESLSQ MLSMGFSDEG GWLTRLLQTK NYDIGAALDT IQYSKHPPPL
    交叉反应
    人, 小鼠
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    SQSTM1 (AAH03139.1, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    2C11
    亚型
    IgG2a
    Top Product
    Discover our top product SQSTM1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Korwitz, Merkwirth, Richter-Dennerlein, Tröder, Sprenger, Quirós, López-Otín, Rugarli, Langer: "Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria." in: The Journal of cell biology, Vol. 212, Issue 2, pp. 157-66, (2016) (PubMed).

    Sydow, Hochgräfe, Könen, Cadinu, Matenia, Petrova, Joseph, Dennissen, Mandelkow: "Age-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD." in: Acta neuropathologica communications, Vol. 4, pp. 17, (2016) (PubMed).

    Winner, Beard, Hassiotis, Lau, Luck, Hopwood, Hemsley: "A Preclinical Study Evaluating AAVrh10-Based Gene Therapy for Sanfilippo Syndrome." in: Human gene therapy, Vol. 27, Issue 5, pp. 363-75, (2016) (PubMed).

    He, Hamm, Reddy, Sams, Peliciari-Garcia, McGinnis, Bailey, Chow, Rowe, Chatham, Young: "Biotinylation: a novel posttranslational modification linking cell autonomous circadian clocks with metabolism." in: American journal of physiology. Heart and circulatory physiology, Vol. 310, Issue 11, pp. H1520-32, (2016) (PubMed).

    Jin, Hong, Park, Chang, Hong, Park, Lee: "Inhibition of JNK-mediated autophagy enhances NSCLC cell sensitivity to mTORC1/2 inhibitors." in: Scientific reports, Vol. 6, pp. 28945, (2016) (PubMed).

    Aydinlik, Erkisa, Cevatemre, Sarimahmut, Dere, Ari, Ulukaya: "Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line." in: Biochimica et biophysica acta, Vol. 1861, Issue 2, pp. 49-57, (2016) (PubMed).

    Redmann, Benavides, Berryhill, Wani, Ouyang, Johnson, Ravi, Barnes, Darley-Usmar, Zhang: "Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons." in: Redox biology, Vol. 11, pp. 73-81, (2016) (PubMed).

    Garofalo, Iovine, Kuryk, Capasso, Hirvinen, Vitale, Yliperttula, Bevilacqua, Cerullo: "Oncolytic Adenovirus Loaded with L-carnosine as Novel Strategy to Enhance the Antitumor Activity." in: Molecular cancer therapeutics, Vol. 15, Issue 4, pp. 651-60, (2016) (PubMed).

    Morgan, Thorburn: "Measuring Autophagy in the Context of Cancer." in: Advances in experimental medicine and biology, Vol. 899, pp. 121-43, (2016) (PubMed).

    Wilson, Nikolic, Kentish, Shalini, Hatzinikolas, Page, Dorstyn, Kumar: "Sex-specific alterations in glucose homeostasis and metabolic parameters during ageing of caspase-2-deficient mice." in: Cell death discovery, Vol. 2, pp. 16009, (2016) (PubMed).

    Conlon, Thomas, Fedotova, Hernandez-Ono, Di Paolo, Chan, Ruggles, Gibeley, Liu, Ginsberg: "Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis." in: The Journal of clinical investigation, Vol. 126, Issue 10, pp. 3852-3867, (2016) (PubMed).

    de Luxán-Delgado, Caballero, Potes, Rubio-González, Rodríguez, Gutiérrez-Rodríguez, Solano, Coto-Montes: "Melatonin administration decreases adipogenesis in the liver of ob/ob mice through autophagy modulation." in: Journal of pineal research, Vol. 56, Issue 2, pp. 126-33, (2015) (PubMed).

    Niso-Santano, Malik, Pietrocola, Bravo-San Pedro, Mariño, Cianfanelli, Ben-Younès, Troncoso, Markaki, Sica, Izzo, Chaba, Bauvy, Dupont, Kepp, Rockenfeller, Wolinski, Madeo, Lavandero, Codogno, Harper et al.: "Unsaturated fatty acids induce non-canonical autophagy. ..." in: The EMBO journal, (2015) (PubMed).

    Kucukgul, Ozler, Inci, Karakas, Irmak, Gozuacik, Taralp, Koc: "3D bioprinting of biomimetic aortic vascular constructs with self-supporting cells." in: Biotechnology and bioengineering, Vol. 112, Issue 4, pp. 811-21, (2015) (PubMed).

    Li, Shi, He, Hu, Wang, Zhang, Chan, Chen: "Streptococcus pneumoniae induces autophagy through the inhibition of the PI3K-I/Akt/mTOR pathway and ROS hypergeneration in A549 cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122753, (2015) (PubMed).

    Porta, Kwong, Trojanowski, Lee: "Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 4, pp. 380-7, (2015) (PubMed).

    Yang, Peng, Ni, Li, Shi, Ding, Fan: "Basal Autophagy and Feedback Activation of Akt Are Associated with Resistance to Metformin-Induced Inhibition of Hepatic Tumor Cell Growth." in: PLoS ONE, Vol. 10, Issue 6, pp. e0130953, (2015) (PubMed).

    Dou, Xu, Donahue, Shimi, Pan, Zhu, Ivanov, Capell, Drake, Shah, Catanzaro, Ricketts, Lamark, Adam, Marmorstein, Zong, Johansen, Goldman, Adams, Berger: "Autophagy mediates degradation of nuclear lamina." in: Nature, Vol. 527, Issue 7576, pp. 105-9, (2015) (PubMed).

    Cinque, Forrester, Bartolomeo, Svelto, Venditti, Montefusco, Polishchuk, Nusco, Rossi, Medina, Polishchuk, De Matteis, Settembre: "FGF signalling regulates bone growth through autophagy." in: Nature, Vol. 528, Issue 7581, pp. 272-5, (2015) (PubMed).

    Tung, Wang, Hsu, Hu, Her, Huang, Liao: "Presenilin-1 regulates the expression of p62 to govern p62-dependent tau degradation." in: Molecular neurobiology, Vol. 49, Issue 1, pp. 10-27, (2014) (PubMed).

  • 抗原
    SQSTM1 (Sequestosome 1 (SQSTM1))
    别名
    SQSTM1 (SQSTM1 产品)
    背景
    Full Gene Name: sequestosome 1
    Synonyms: A170,OSIL,PDB3,ZIP3,p60,p62,p62B
    基因ID
    8878
    途径
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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