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RRM2 抗体 (AA 1-110)

RRM2 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
产品编号 ABIN562744
发货至: 中国
  • 抗原 See all RRM2 抗体
    RRM2 (Ribonucleotide Reductase M2 (RRM2))
    抗原表位
    • 15
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-110
    适用
    • 54
    • 14
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 50
    • 4
    小鼠
    克隆类型
    • 42
    • 12
    单克隆
    标记
    • 22
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRM2 antibody is un-conjugated
    应用范围
    • 37
    • 13
    • 13
    • 13
    • 9
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Mouse monoclonal antibody raised against a partial recombinant RRM2.
    序列
    MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    RRM2 (NP_001025, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    1E1
    亚型
    IgG1
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Castelblanco, Zafon, Maravall, Gallel, Martinez, Capel, Bella, Halperin, Temprana, Iglesias, Puig-Domingo, Robledo, Matias-Guiu, Mauricio: "APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions." in: Thyroid : official journal of the American Thyroid Association, Vol. 27, Issue 1, pp. 59-66, (2016) (PubMed).

    Kim, Park, Joo, Shen, Hong, Kim, Singh, Lee, Shin: "RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress." in: Cancer letters, Vol. 346, Issue 2, pp. 249-56, (2014) (PubMed).

    Yoshida, Tsunoda, Doi, Tanaka, Fujimoto, Machida, Ota, Koyanagi, Takashima, Sasazuki, Kuroki, Iwasaki, Shirasawa: "KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines." in: Anticancer research, Vol. 31, Issue 7, pp. 2535-9, (2011) (PubMed).

    Zhou, Snyder, Lieberman: "Epstein-Barr virus episome stability is coupled to a delay in replication timing." in: Journal of virology, Vol. 83, Issue 5, pp. 2154-62, (2009) (PubMed).

    Tang, Deng, Wang, Dai, Wang, Jiang, Li, Li, Sheng, Wu, Li, Zeng et al.: "Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in ..." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 11, pp. 1952-67, (2007) (PubMed).

  • 抗原
    RRM2 (Ribonucleotide Reductase M2 (RRM2))
    别名
    RRM2 (RRM2 产品)
    别名
    R2 antibody, RR2 antibody, RR2M antibody, AA407299 antibody, rrm2 antibody, rr2m antibody, cb111 antibody, chunp6884 antibody, r2 antibody, ribonucleotide reductase regulatory subunit M2 antibody, ribonucleotide reductase M2 antibody, ribonucleotide reductase M2, gene 2 L homeolog antibody, ribonucleotide reductase M2, gene 1 antibody, ribonucleotide reductase M2 polypeptide antibody, RRM2 antibody, Rrm2 antibody, rrm2.2.L antibody, rrm2.1 antibody, rrm2 antibody
    背景
    Full Gene Name: ribonucleotide reductase M2 polypeptide
    Synonyms: R2,RR2M
    基因ID
    6241
    NCBI登录号
    NM_001034
    途径
    Mitotic G1-G1/S Phases
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