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Rab6-GTP (Gln72Leu-Mutant) 抗体 (Atto 488)

ABIN5564232 产品详细信息, 供应商: Log in to see
抗原
抗原表位
Gln72Leu-Mutant
3
适用
Fruit Fly (Drosophila melanogaster), 人, 小鼠
3
3
3
宿主
Human
2
1
抗体类型
Recombinant Antibody
克隆类型 (克隆位点)
单克隆 ()
标记
Atto 488
1
应用范围
Immunocytochemistry (ICC)
3
1
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免疫原 Recombinant Rab6AQ72L, a GTP-locked mutant of Rab6A in which Gln72 is replaced by Leu.
克隆位点 AA2
亚型 IgG2
特异性 Recognizes human, mouse and Drosophila GTP-bound Rab6a and Rab6b and mutant Rab6Q72L.
交叉反应 Fruit Fly (Drosophila melanogaster), 人, 小鼠
交叉反应 (详细) Does not detect Rab6•GDP.
纯度 >95 % (SDS-PAGE)
背景 Rab6 is involved in protein transport. It is a regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER).
UniProt P20340
说明

anti-Rab6-GTP, monoclonal antibody (recombinant) (AA2) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the human lgG2 Fc domain. anti-Rab6-GTP, monoclonal antibody (recombinant) (AA2) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.

限制 仅限研究用
状态 Liquid
浓度 1 mg/mL
缓冲液 In PBS containing 0.02 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C
储存方法 Short Term Storage: +4°C
Long Term Storage: +4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.
有效期 12 months