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MAD2L1 抗体 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 3-13)

Details for Product anti-MAD2L1 Antibody No. ABIN5556684, 供应商: Log in to see
抗原
  • cb408
  • zgc:112133
  • MAD2L1
  • mad2
  • XMad2
  • AA673185
  • MAD2
  • HSMAD2
  • MAD2 mitotic arrest deficient-like 1 (yeast)
  • MAD2 mitotic arrest deficient-like 1
  • MAD2L1
  • mad2l1
  • LOC100218172
  • Mad2l1
抗原表位
AA 3-13
19
8
6
6
4
4
4
3
3
3
2
2
1
1
1
1
1
1
适用

120
36
33
9
6
5
4
4
4
3
3
2
2
1
宿主

71
34
15
1
克隆类型
多克隆
标记
This MAD2L1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
应用范围
Enzyme Immunoassay (EIA), Western Blotting (WB)
102
46
23
22
21
20
13
6
1
1
1
1
1
1
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免疫原 This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues 3-13 of Human MAD2L1 protein.
序列 Human MAD2L1, 205 amino acids, predicated MW 23.5 kDa. 1 malqlsreqg itlrgsaeiv aeffsfgins ilyqrgiyps etftrvqkyg ltllvttdle 61 likylnnvve qlkdwlykcs vqklvvvisn iesgevlerw qfdiecdkta kddsapreks 121 qkaiqdeirs virqitatvt flpllevscs fdlliytdkd lvvpekwees gpqfitnsee 181 vrlrsfttti hkvnsmvayk ipvnd
特异性 This affinity purified antibody is directed against human MAD2L1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from human, dog, macaque, chimpanzee and gecko based on 100 % homology for the immunogen sequence. Cross reactivity with MAD2L1 may occur from mouse and chicken sources, as only a two amino acid residue change is found within the immunogen sequence (90 % positive by BLAST). Cross reactivity with MAD2L1 homologues from other sources has not been determined.
产品特性 Concentration: 1.19 mg/mL (by UV absorbance at 280 nm)
纯化方法 Immunoaffinity chromatography.
别名 MAD2L1 (MAD2L1 Antibody 摘要)
背景 MAD2L1 (also called mitotic spindle assembly checkpoint protein, MAD2A, MAD2-like 1 and HsMAD2) is a component of the mitotic spindle assembly checkpoint monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete. MAD2L1 inhibits the activity of the anaphase-promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. This protein has a nuclear localization.Synonyms: MAD2, Mitotic spindle assembly checkpoint protein MAD2A
基因ID 4085
NCBI登录号 NP_002349
UniProt Q13257
研究领域 Cell Cycle
应用备注 This affinity purified antibody has been tested for use in ELISA (1: 2,000-1: 10,000) and byWestern blot (1: 500-1: 2,000). Specific conditions for reactivity should be optimized by theend user. Expect a predominant band at approx. 24 kDa corresponding to full length protein bywestern blotting in the appropriate cell lysate or extract.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
浓度 1.19 mg/mL
缓冲液 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 This product is photosensitive and should be protected from light
储存条件 4 °C
储存方法 Store undiluted at 2-8 °C. DO NOT FREEZE!