Nicalin 抗体 (C-Term)
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- 抗原 See all Nicalin (NCLN) 抗体
- Nicalin (NCLN)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Nicalin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- Multiple isoforms of NCLN are known to exist.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 18 amino acid synthetic peptide near the carboxy terminus of Human NCLN
- 亚型
- IgG
- Top Product
- Discover our top product NCLN Primary Antibody
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anti-Nicalin (NCLN) (AA 44-144) antibody
NCLN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nicalin (NCLN) (N-Term) antibodyNCLN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nicalin (NCLN) (AA 214-522) antibodyNCLN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1-2 μg/ml.
Positive Control: Mouse heart tissue lysate.
Immunofluorescence: Start at 2.5 μg/ml.
Immunohistochemistry on Paraffin Sections: Start at 2.5 μg/ml.
Optimal working dilution should be determined by the investigator. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Nicalin (NCLN)
- 别名
- Nicalin (NCLN 产品)
- 背景
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Nicalin, along with its binding partner Nomo, is a novel signaling antagonist to Nodals, signaling factors of the TGF-beta superfamily that play a key role in vertebrate development. Nicalin is distantly related to Nicastrin, a component of the Alzheimer’s disease-associated gamma-secretase, and is thought to have a similar function. Another protein, TMEM147, has also been recently identified as associating with Nicalin and NOMO as part of the gamma-secretase-like complex.
Synonyms: NCLN - 基因ID
- 56926
- NCBI登录号
- NP_064555
- UniProt
- Q969V3
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