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PRR5L 抗体 (Center)

PRR5L 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783444
发货至: 中国
  • 抗原 See all PRR5L 抗体
    PRR5L (Proline Rich 5 Like (PRR5L))
    抗原表位
    • 1
    • 1
    Center
    适用
    • 3
    • 1
    宿主
    • 3
    克隆类型
    • 3
    多克隆
    标记
    • 3
    This PRR5L antibody is un-conjugated
    应用范围
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects PRR5L at Center. At least three isoforms of PRR5L are known to exist, this antibody will recognize only isoforms a and b. PRR5L antibody will not cross-react with PPR5.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    17 amino acid peptide near the center of human PRR5L
    Top Product
    Discover our top product PRR5L Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原
    PRR5L (Proline Rich 5 Like (PRR5L))
    别名
    PRR5L (PRR5L 产品)
    别名
    PROTOR2 antibody, 2600010E01Rik antibody, 4833411O04Rik antibody, Protor-2 antibody, Protor2 antibody, RGD1309969 antibody, PRR5L antibody, FLJ14213 antibody, proline rich 5 like antibody, PRR5L antibody, Prr5l antibody, prr5l antibody
    背景
    Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2). PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2. Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.Synonyms: FLJ14213, PROTOR2, Proline-rich protein 5-like, Protein observed with Rictor-2
    基因ID
    79899
    NCBI登录号
    NP_001153639
    UniProt
    Q6MZQ0
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