HCST 抗体 (Hematopoietic Cell Signal Transducer) (C-Term)

Details for Product anti-HCST Antibody No. ABIN5553692, 供应商: Log in to see
抗原
  • HCST
  • DAP10
  • KAP10
  • PIK3AP
  • Dap10
  • hematopoietic cell signal transducer
  • HCST
  • hcst
  • Hcst
抗原表位
C-Term
12
2
1
1
1
适用

30
1
1
1
宿主
山羊
15
15
克隆类型
多克隆
标记
This HCST antibody is un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Enzyme Immunoassay (EIA), Western Blotting (WB)
15
13
13
3
选项
Supplier
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免疫原 Peptide with sequence C-RSPAQEDGKVYIN, from the C Terminus of the protein sequence
特异性 This antibody is expected to recognize isoform 1 (NP_055081.1) but it may recognize isoform 2 lacking residue E81 (NP_001007470.1).
交叉反应 (详细) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
纯化方法 Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography
别名 DAP10 / HCST (HCST Antibody 摘要)
背景 HCST is a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. It may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D and may activate phosphatidylinositol 3-kinase dependent signaling pathways. The receptor complex containing HCST may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms.Synonyms: DNAX-activation protein 10, Hematopoietic cell signal transducer, KAP10, Membrane protein DAP10, PIK3AP, Transmembrane adapter protein KAP10
基因ID 10870
NCBI登录号 NP_001007470
UniProt Q9UBK5
应用备注 Peptide ELISA: 1/128000. Western Blot: 0.2-0.6 μg/mL. Approx 40 kDa band observed in Human spleen lysates (calculated MW of 9.0 kDaaccording to NP_055081.1). An additional band of unknown identity was also consistentlyobserved at 100 kDa. This band was successfully blocked by incubation with theimmunising peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
浓度 0.5 mg/mL
缓冲液 Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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