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LIM Domain Binding 3 Protein 抗体 (Internal Region)

LDB3 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374603
发货至: 中国
  • 抗原 See all LIM Domain Binding 3 Protein (LDB3) 抗体
    LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 26
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 23
    • 4
    • 1
    山羊
    克隆类型
    • 25
    • 3
    多克隆
    标记
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    This LIM Domain Binding 3 Protein antibody is un-conjugated
    应用范围
    • 27
    • 19
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to LDB3.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine, Porcine.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence C-KSQNKPEDEADE, from the internal region of the protein sequence
    Top Product
    Discover our top product LDB3 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/2000. Western Blot: 0.01 - 0.03 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0,5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))
    别名
    LDB3 (LDB3 产品)
    别名
    CMD1C antibody, CYPHER antibody, LDB3Z1 antibody, LDB3Z4 antibody, LVNC3 antibody, MFM4 antibody, ORACLE antibody, PDLIM6 antibody, ZASP antibody, AW742271 antibody, ldb3l antibody, zgc:55814 antibody, wu:fi31d08 antibody, ldb3 antibody, MGC52706 antibody, MGC75668 antibody, RGD1564875 antibody, LDB3 antibody, cypher antibody, hm:zehn1639 antibody, zehn1639 antibody, LIM domain binding 3 antibody, LIM domain binding 3b antibody, LIM domain binding 3 S homeolog antibody, LIM domain binding 3a antibody, LDB3 antibody, Ldb3 antibody, ldb3b antibody, ldb3.S antibody, ldb3 antibody, ldb3a antibody
    背景
    LDB3 (LIM domain-binding protein 3) may function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton. It interactes with various PKC isoforms and with the C-terminal region of ACTN2 via its LIM and PDZ domains respectively. It also interacts with MYOZ1, MYOZ2 and MYOZ3. 6 isoforms are produced by alternative splicing. Defects in LDB3 are a cause of dilated cardiomyopathy 1A, a disorder characterized by cardiac dilation and reduced systolic function, as well as ZASP-related myofibrillar myopathy, an autosomal dominant myopathy that is characterized by distal muscle weakness with signs of cardiomyopathy and neuropathy.Synonyms: KIAA0613, LIM domain-binding protein 3, ZASP
    基因ID
    11155, 9606
    UniProt
    O75112
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