LIM Domain Binding 3 Protein 抗体 (Internal Region)
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- 抗原 See all LIM Domain Binding 3 Protein (LDB3) 抗体
- LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This LIM Domain Binding 3 Protein antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody reacts to LDB3.
- 交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine, Porcine.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 免疫原
- Peptide with sequence C-KSQNKPEDEADE, from the internal region of the protein sequence
- Top Product
- Discover our top product LDB3 Primary Antibody
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- 应用备注
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Peptide ELISA: 1/2000. Western Blot: 0.01 - 0.03 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0,5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))
- 别名
- LDB3 (LDB3 产品)
- 别名
- CMD1C antibody, CYPHER antibody, LDB3Z1 antibody, LDB3Z4 antibody, LVNC3 antibody, MFM4 antibody, ORACLE antibody, PDLIM6 antibody, ZASP antibody, AW742271 antibody, ldb3l antibody, zgc:55814 antibody, wu:fi31d08 antibody, ldb3 antibody, MGC52706 antibody, MGC75668 antibody, RGD1564875 antibody, LDB3 antibody, cypher antibody, hm:zehn1639 antibody, zehn1639 antibody, LIM domain binding 3 antibody, LIM domain binding 3b antibody, LIM domain binding 3 S homeolog antibody, LIM domain binding 3a antibody, LDB3 antibody, Ldb3 antibody, ldb3b antibody, ldb3.S antibody, ldb3 antibody, ldb3a antibody
- 背景
- LDB3 (LIM domain-binding protein 3) may function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton. It interactes with various PKC isoforms and with the C-terminal region of ACTN2 via its LIM and PDZ domains respectively. It also interacts with MYOZ1, MYOZ2 and MYOZ3. 6 isoforms are produced by alternative splicing. Defects in LDB3 are a cause of dilated cardiomyopathy 1A, a disorder characterized by cardiac dilation and reduced systolic function, as well as ZASP-related myofibrillar myopathy, an autosomal dominant myopathy that is characterized by distal muscle weakness with signs of cardiomyopathy and neuropathy.Synonyms: KIAA0613, LIM domain-binding protein 3, ZASP
- 基因ID
- 11155, 9606
- UniProt
- O75112
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