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CBL 抗体 (C-Term)

CBL 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374153
发货至: 中国
  • 抗原 See all CBL 抗体
    CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
    抗原表位
    • 28
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    • 17
    • 9
    • 7
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    • 5
    • 3
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    C-Term
    适用
    • 171
    • 77
    • 65
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, Pig
    宿主
    • 151
    • 18
    • 3
    • 1
    山羊
    克隆类型
    • 142
    • 31
    多克隆
    标记
    • 76
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    This CBL antibody is un-conjugated
    应用范围
    • 82
    • 52
    • 52
    • 49
    • 32
    • 25
    • 21
    • 16
    • 12
    • 10
    • 9
    • 3
    • 1
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    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-REFVSISSPA HVAT
    特异性
    This antibody detects RNF55 / CBL at C-term.
    交叉反应 (详细)
    Species reactivity (expected):Human, Rat, Dog, Pig, Cow.
    Species reactivity (tested):Mouse.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide from C Terminus of the protein sequence according to NP_005179.2 Genename: CBL
    Top Product
    Discover our top product CBL Primary Antibody
  • 应用备注
    Peptide ELISA: Limit dilution 1: 32000. Western blot: 1-3 μg/mL. Approx 120 kDa band seen in 3T3 lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
    别名
    CBL / RNF55 (CBL 产品)
    别名
    4732447J05Rik antibody, Cbl-2 antibody, c-Cbl antibody, cbl antibody, C-CBL antibody, CBL2 antibody, FRA11B antibody, NSLL antibody, RNF55 antibody, c-cbl-like antibody, RGD1561386 antibody, Casitas B-lineage lymphoma antibody, Cbl proto-oncogene antibody, Cbl antibody, CBL antibody
    背景
    Cbl (also designated the c-Cbl proto-oncogene, E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene and RING finger protein 55) has been identified as the cellular homolog of the v-Cbl oncogene isolated from an NFS/N mouse that developed a pre-B cell lymphoma following infection with the replication-competent Cas Br-M murine leukemic virus. c-Cbl is expressed at relatively high levels in a wide range of hematopoietic tumor cell lines as well as in normal tissues such as thymus and testis. The c-Cbl gene product has been identified as a cytoplasmic protein with apparent DNA binding and dimerization domains characteristic of transcription factors. A single c-Cbl locus termed CBL2 has been mapped to human chromosome 11q23. This region of chromosome 11 is involved in translocations and deletions in a broad range of leukemias, c-Cbl has been found to be translocated from chromosome 11 in leukemias with either t(4,11) or t(11,14) abnormalities.Synonyms: CBL2, Casitas B-lineage lymphoma proto-oncogene, E3 ubiquitin-protein ligase CBL, Proto-oncogene c-CBL, RING finger protein 55, Signal transduction protein CBL, c-CBL
    基因ID
    867
    NCBI登录号
    NP_005179
    UniProt
    P22681
    途径
    TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals
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