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DUSP1 抗体 (C-Term)

DUSP1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374121
发货至: 中国
  • 抗原 See all DUSP1 抗体
    DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))
    抗原表位
    • 17
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 85
    • 35
    • 34
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬
    宿主
    • 81
    • 3
    • 1
    山羊
    克隆类型
    • 74
    • 11
    多克隆
    标记
    • 29
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DUSP1 antibody is un-conjugated
    应用范围
    • 64
    • 37
    • 27
    • 26
    • 14
    • 11
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    序列
    SYLQSPITTS PSC
    特异性
    This antibody detects DUSP1 at C-term.
    交叉反应 (详细)
    Species reactivity (expected):Canine (Dog), Bovine.
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Synthetic peptide from C-Terminus of Human DUSP1 (NP_004408.1) Genename: DUSP1
    Top Product
    Discover our top product DUSP1 Primary Antibody
  • 应用备注
    Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.3-1 μg/mL. Approx.40 kDa band observed in Human lysates of HeLa(calculated MW of 39.0 kDa according to NP_004408.1). Immunohistochemistry: 3-5 μg/mL. In paraffin embedded Human Prostate shows strongcytoplasm staining of secretory cells in the glands.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))
    别名
    DUSP1 / MKP1 (DUSP1 产品)
    别名
    CL100 antibody, HVH1 antibody, MKP-1 antibody, MKP1 antibody, PTPN10 antibody, 3CH134 antibody, Mkp1 antibody, Ptpn16 antibody, DUSP1 antibody, U19515 antibody, erp antibody, mkp-1 antibody, cb269 antibody, sb:cb269 antibody, zgc:55920 antibody, id:ibd2586 antibody, wu:fd19g02 antibody, wu:fe50g09 antibody, XCL100 antibody, dual specificity phosphatase 1 antibody, dual specificity phosphatase 1 S homeolog antibody, DUSP1 antibody, Dusp1 antibody, dusp1 antibody, dusp1.S antibody
    背景
    The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.Synonyms: CL100, Dual specificity protein phosphatase 1, Dual specificity protein phosphatase hVH1, MAP kinase phosphatase 1, MKP-1, PTPN10, Protein-tyrosine phosphatase CL100, VH1
    基因ID
    1843
    NCBI登录号
    NP_004408
    UniProt
    P28562
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