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- 抗原 See all APEX2 抗体
- APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
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抗原表位
- AA 102-210
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APEX2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for DNA-(apurinic or apyrimidinic site) lyase 2(APEX2) detection. Tested with WB in Human,Rat.
- 交叉反应 （详细）
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for DNA-(apurinic or apyrimidinic site) lyase 2(APEX2) detection. Tested with WB in Human,Rat.
Gene Name: APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Protein Name: DNA-(apurinic or apyrimidinic site) lyase 2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human APEX2 recombinant protein (Position: L102-A210). Human APEX2 shares 91.7% amino acid (aa) sequence identity with mouse APEX2.
- 亚型
- IgG
- Top Product
- Discover our top product APEX2 Primary Antibody
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anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 143-171) antibody
APEX2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB23043 unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 1-518) antibodyAPEX2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) antibodyAPEX2 适用: 人 WB, IHC, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 301-400) antibodyAPEX2 适用: 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
- 别名
- APEX2 (APEX2 产品)
- 别名
- APE2 antibody, APEXL2 antibody, XTH2 antibody, ape2 antibody, apexl2 antibody, xth2 antibody, zgc:55889 antibody, C430040P13Rik antibody, apurinic/apyrimidinic endodeoxyribonuclease 2 antibody, APEX nuclease (apurinic/apyrimidinic endonuclease) 2 antibody, apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog antibody, apurinic/apyrimidinic endonuclease 2 antibody, APEX2 antibody, apex2 antibody, apex2.L antibody, Apex2 antibody
- 背景
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APEX2, also called apurinic/apyrimidinic endonuclease like-2, is a member of the apurinic/apyrimidinic (AP) family of endonucleases that initiate the repair of AP sites formed by spontaneous hydrolysis of the N-glycosylic bond, mutagen-induced base release, or damaged-base excision by a DNA repair glycosylase. RT-PCR detected APEX2 expression in HeLa cells, Jurkat cells, and human kidney, brain and fetal brain tissue. The APEX2 gene is mapped to chromosome Xp11.21. APEX2 participates in both nuclear and mitochondrial base excision repair (BER) and it can play a role in processing 3-prime-damaged termini or 3-prime-mismatched nucleotides. Additionally, APEX2 displayed weaker AP site-specific and 3-prime nuclease activities compared to APEX1.
Synonyms: AP endonuclease XTH2 | APE2 | APE2 | XTH2 | APEX nuclease-like 2 | APEX2 | APEXL 2 | APEXL2 | Q9UBZ4 | XTH 2 - 基因ID
- 27301
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