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- 抗原 See all TRKA (NTRK1) 抗体
- TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
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抗原表位
- AA 71-90, N-Term
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRKA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for High affinity nerve growth factor receptor(NTRK1) detection. Tested with WB in Mouse,Rat.
- 序列
- LYVENQQHLQ RLEFEDLQGL
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for High affinity nerve growth factor receptor(NTRK1) detection. Tested with WB in Mouse,Rat.
Gene Name: neurotrophic tyrosine kinase, receptor, type 1
Protein Name: High affinity nerve growth factor receptor - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse TrkA(71-90aa LYVENQQHLQRLEFEDLQGL), different from the related rat sequence by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NTRK1 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Sodium azide, Thimerosal (Merthiolate)
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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The interactions between nerve growth factor and gonadotrophins in bovine oviduct." in: Animal reproduction science, Vol. 149, Issue 3-4, pp. 117-23, (2014) (PubMed).
: "Accumulation of nerve growth factor and its receptors in the uterus and dorsal root ganglia in a mouse model of adenomyosis." in: Reproductive biology and endocrinology : RB&E, Vol. 9, pp. 30, (2011) (PubMed).
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The interactions between nerve growth factor and gonadotrophins in bovine oviduct." in: Animal reproduction science, Vol. 149, Issue 3-4, pp. 117-23, (2014) (PubMed).
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- 抗原
- TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
- 别名
- NTRK1 (NTRK1 产品)
- 别名
- MTC antibody, TRK antibody, TRK1 antibody, TRKA antibody, Trk-A antibody, p140-TrkA antibody, CDHF12 antibody, CDHR16 antibody, HSCR1 antibody, MEN2A antibody, MEN2B antibody, MTC1 antibody, PTC antibody, RET-ELE1 antibody, RET51 antibody, Trk antibody, C80751 antibody, Tkr antibody, TrkA antibody, trk antibody, trka antibody, CTRKA antibody, trkA antibody, neurotrophic receptor tyrosine kinase 1 antibody, ret proto-oncogene antibody, neurotrophic tyrosine kinase, receptor, type 1 antibody, NTRK1 antibody, RET antibody, Ntrk1 antibody, ntrk1 antibody
- 背景
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Neurotrophic tyrosine kinase receptor type 1, also called Trk-A, is a protein that in humans is encoded by the NTRK1 gene. The NTKR1 gene encodes the neurotrophic tyrosine kinase-1 receptor and belongs to a family of nerve growth factor receptors whose ligands include neurotrophins. This gene is mapped to 1q23.1. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Synonyms: CIPA antibody|DKFZp781I14186 antibody|gp140trk antibody|High affinity nerve growth factor receptor antibody|High affinity nerve growth factor receptor precursor antibody|MTC antibody|Neurotrophic tyrosine kinase receptor type 1 antibody|Ntrk 1 antibody|Ntrk1 antibody|NTRK1_HUMAN antibody|Oncogene TRK antibody|p140 TrkA antibody|p140-TrkA antibody|TRK 1 antibody|Trk A antibody|TRK antibody|Trk-A antibody|TRK1 antibody|TRK1 transforming tyrosine kinase protein antibody|TRK1-transforming tyrosine kinase protein antibody|Tropomyosin-related kinase A antibody|Tyrosine kinase receptor A antibody|Tyrosine kinase receptor antibody|Tyrosine Receptor Kinase A antibody - 途径
- RTK signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process
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