SQSTM1 抗体 (AA 1-440)
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- 抗原 See all SQSTM1 抗体
- SQSTM1 (Sequestosome 1 (SQSTM1))
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抗原表位
- AA 1-440
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SQSTM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Mouse monoclonal antibody raised against a full-length recombinant SQSTM1.
- 序列
- MASLTVKAYL LGKEDAAREI RRFSFCCSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN MVHPNVICDG CNGPVVGTRY KCSVCPDYDL CSVCEGKGLH RGHTKLAFPS PFGHLSEGFS HSRWLRKVKH GHFGWPGWEM GPPGNWSPRP PRAGEARPGP TAESASGPSE DPSVNFLKNV GESVAAALSP LGIEVDIDVE HGGKRSRLTP VSPESSSTEE KSSSQPSSCC SDPSKPGGNV EGATQSLAEQ MRKIALESEG RPEEQMESDN CSGGDDDWTH LSSKEVDPST GELQSLQMPE SEGPSSLDPS QEGPTGLKEA ALYPHLPPEA DPRLIESLSQ MLSMGFSDEG GWLTRLLQTK NYDIGAALDT IQYSKHPPPL
- 交叉反应
- 人
- 产品特性
- Antibody Reactive Against Recombinant Protein.
- 免疫原
- SQSTM1 (AAH03139.1, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- 克隆位点
- 1C9
- 亚型
- IgG3
- Top Product
- Discover our top product SQSTM1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- In 1x PBS, pH 7.4
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling." in: Nature medicine, Vol. 22, Issue 1, pp. 46-53, (2016) (PubMed).
: "Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation." in: Cell death & disease, Vol. 4, pp. e638, (2013) (PubMed).
: "BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway." in: Biochemical pharmacology, Vol. 80, Issue 8, pp. 1160-9, (2010) (PubMed).
: "A role for NBR1 in autophagosomal degradation of ubiquitinated substrates." in: Molecular cell, Vol. 33, Issue 4, pp. 505-16, (2009) (PubMed).
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Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling." in: Nature medicine, Vol. 22, Issue 1, pp. 46-53, (2016) (PubMed).
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- 抗原
- SQSTM1 (Sequestosome 1 (SQSTM1))
- 别名
- SQSTM1 (SQSTM1 产品)
- 别名
- SQSTM1 antibody, sqstm1 antibody, MGC79491 antibody, A170 antibody, OSIL antibody, PDB3 antibody, ZIP3 antibody, p60 antibody, p62 antibody, p62B antibody, OSF-6 antibody, Osi antibody, STAP antibody, ZIP antibody, sb:cb621 antibody, zgc:85784 antibody, sequestosome 1 antibody, sequestosome 1 L homeolog antibody, SQSTM1 antibody, sqstm1 antibody, Sqstm1 antibody, sqstm1.L antibody
- 背景
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Full Gene Name: sequestosome 1
Synonyms: A170,OSIL,PDB3,ZIP3,p60,p62,p62B - 基因ID
- 8878
- 途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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