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Rhotekin 抗体 (Middle Region)

RTKN 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN503878
发货至: 中国
  • 抗原 See all Rhotekin (RTKN) 抗体
    Rhotekin (RTKN)
    抗原表位
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 25
    • 9
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔
    宿主
    • 21
    • 5
    克隆类型
    • 22
    • 4
    多克隆
    标记
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Rhotekin antibody is un-conjugated
    应用范围
    • 17
    • 9
    • 7
    • 5
    • 5
    • 3
    Western Blotting (WB)
    序列
    IETPAPRKPP QALAKQGSLY HEMAIEPLDD IAAVTDILTQ REGARLETPP
    预测反应
    Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against RTKN. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human RTKN
    Top Product
    Discover our top product RTKN Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 563 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Rhotekin (RTKN)
    别名
    RTKN (RTKN 产品)
    别名
    RTKN antibody, rhotekin antibody, RTKN antibody, rtkn antibody, Rtkn antibody
    背景
    RTKN mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. RTKN may play a novel role in the organization of septin structures.This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: -
    Protein Interaction Partner: YWHAB, RHO1, APP, RHOA, UBC, TAX1BP3, SMURF1, GOPC, RAC2, TGFBR1, RHOC, RTN4R,
    Protein Size: 563
    分子量
    63 kDa
    基因ID
    6242
    NCBI登录号
    NM_001015055, NP_001015055
    UniProt
    Q9BST9
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