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Carabin 抗体 (N-Term)

TBC1D10C 适用: 人, 大鼠, 犬, 马, Cow, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN503788
发货至: 中国
  • 抗原 See all Carabin (TBC1D10C) 抗体
    Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))
    抗原表位
    • 5
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 犬, 马, Cow, 豚鼠, Pig
    宿主
    • 9
    • 1
    克隆类型
    • 10
    多克隆
    标记
    • 10
    This Carabin antibody is un-conjugated
    应用范围
    • 10
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    MAQALGEDLV QPPELQDDSS SLGSDSELSG PGPYRQADRY GFIGGSSAEP
    预测反应
    Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Pig: 93%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against TBC1D10C. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human TBC1D10C
    Top Product
    Discover our top product TBC1D10C Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 446 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))
    别名
    TBC1D10C (TBC1D10C 产品)
    别名
    CARABIN antibody, EPI64C antibody, 1810062O14Rik antibody, AI428527 antibody, RGD1311490 antibody, TBC1 domain family member 10C antibody, TBC1 domain family, member 10c antibody, TBC1 domain family, member 10C antibody, TBC1D10C antibody, Tbc1d10c antibody
    背景
    TBC1D10C inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. TBC1D10C acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM].
    Alias Symbols: FLJ00332, MGC46488, EPI64C, CARABIN
    Protein Interaction Partner: NOTCH2NL, KRTAP13-1, KLHL12, KRTAP5-9, HOXA1, APP, PPP3R2,
    Protein Size: 446
    分子量
    50 kDa
    基因ID
    374403
    NCBI登录号
    NM_198517, NP_940919
    UniProt
    Q8IV04
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