FBXO31 抗体 (Middle Region)
(1 reference)-
- 抗原 See all FBXO31 抗体
- FBXO31 (F-Box Protein 31 (FBXO31))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FBXO31 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VAAAEQPAQC GQGQPFVLPV GVSSRNEDYP RTCRMCFYGT GLIAGHGFTS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against FBXO31. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FBXO31
- Top Product
- Discover our top product FBXO31 Primary Antibody
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anti-F-Box Protein 31 (FBXO31) (AA 1-367) antibody
FBXO31 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box Protein 31 (FBXO31) antibodyFBXO31 适用: 人, 犬 WB, FACS 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-F-Box Protein 31 (FBXO31) antibodyFBXO31 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 31 (FBXO31) (AA 151-250) antibodyFBXO31 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 31 (FBXO31) (AA 269-367) antibodyFBXO31 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-F-Box Protein 31 (FBXO31) (AA 431-480) antibodyFBXO31 适用: 人, 小鼠, 犬, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 31 (FBXO31) (AA 395-444) antibodyFBXO31 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 31 (FBXO31) (AA 240-539) antibodyFBXO31 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 31 (FBXO31) (Middle Region) antibodyFBXO31 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 367 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).
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: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).
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- 抗原
- FBXO31 (F-Box Protein 31 (FBXO31))
- 别名
- FBXO31 (FBXO31 产品)
- 别名
- 1110003O08Rik antibody, 2310046N15Rik antibody, Fbx14 antibody, Fbxo14 antibody, FBX14 antibody, FBXO14 antibody, Fbx31 antibody, pp2386 antibody, RGD1561069 antibody, fbx14 antibody, fbx31 antibody, fbxo14 antibody, fbxo31 antibody, F-box protein 31 antibody, F-box protein 31 S homeolog antibody, F-box protein 31 L homeolog antibody, Fbxo31 antibody, FBXO31 antibody, fbxo31 antibody, fbxo31.S antibody, fbxo31.L antibody
- 背景
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FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.Members of the F-box protein family, such as FBXO31, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: DKFZP434B027, DKFZp434J1815, FBX14, FBXO14, FLJ22477, Fbx31, MGC15419, MGC9527, pp2386
Protein Interaction Partner: CDT1, UBE2L6, UBE2D1, CCND1, CUL1, MAP2K6, PARD6A, SKP1, COPS5, RBX1,
Protein Size: 367 - 分子量
- 40 kDa
- 基因ID
- 79791
- NCBI登录号
- NM_024735, NP_079011
- UniProt
- Q5XUX0
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