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PCDHAC1 抗体 (N-Term)

PCDHAC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN503031
发货至: 中国
  • 抗原 See all PCDHAC1 抗体
    PCDHAC1 (Protocadherin alpha Subfamily C, 1 (PCDHAC1))
    抗原表位
    • 15
    • 1
    • 1
    N-Term
    适用
    • 23
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCDHAC1 antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    RVQALDPDEG SNGEVQYSLS NSTQAELRHR FHVHPKSGEV QVAASLGPPE
    预测反应
    Cow: 90%, Dog: 90%, Guinea Pig: 92%, Horse: 90%, Human: 100%, Mouse: 100%, Rabbit: 90%, Rat: 100%, Zebrafish: 90%
    产品特性
    This is a rabbit polyclonal antibody against PCDHAC1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHAC1
    Top Product
    Discover our top product PCDHAC1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 818 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PCDHAC1 (Protocadherin alpha Subfamily C, 1 (PCDHAC1))
    别名
    PCDHAC1 (PCDHAC1 产品)
    别名
    PCDH-ALPHA-C1 antibody, CNRc1 antibody, rCNRvc1 antibody, protocadherin alpha subfamily C, 1 antibody, PCDHAC1 antibody, Pcdhac1 antibody
    背景
    PCDHAC1 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    Alias Symbols: PCDH-ALPHA-C1
    Protein Size: 818
    分子量
    87 kDa
    基因ID
    56135
    NCBI登录号
    NM_031882, NP_114088
    UniProt
    B2RNA7
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