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MITF 抗体 (AA 150-427)

MITF 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal ABM1H91 unconjugated
产品编号 ABIN5027358
发货至: 中国
  • 抗原 See all MITF 抗体
    MITF (Microphthalmia-Associated Transcription Factor (MITF))
    抗原表位
    • 20
    • 15
    • 12
    • 8
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-427
    适用
    • 117
    • 66
    • 26
    • 17
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    宿主
    • 92
    • 39
    • 1
    • 1
    小鼠
    克隆类型
    • 84
    • 49
    单克隆
    标记
    • 64
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MITF antibody is un-conjugated
    应用范围
    • 71
    • 50
    • 44
    • 35
    • 33
    • 18
    • 13
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    小鼠
    纯化方法
    Protein G Chromatography
    免疫原
    A partial length recombinant MITF protein (amino acids 150-427) was used as the immunogen for this antibody.
    克隆位点
    ABM1H91
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MITF Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL, IHC: 10 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    MITF (Microphthalmia-Associated Transcription Factor (MITF))
    别名
    MITF (MITF 产品)
    别名
    MITF antibody, ws2a antibody, mitfa antibody, MITF-A antibody, LOC100313655 antibody, mitfb antibody, CMM8 antibody, MI antibody, WS2 antibody, WS2A antibody, bHLHe32 antibody, BCC2 antibody, Bhlhe32 antibody, Gsfbcc2 antibody, Vitiligo antibody, Wh antibody, bw antibody, mi antibody, vit antibody, MITF-H antibody, MITF-M antibody, CMI9 antibody, melanogenesis associated transcription factor antibody, microphthalmia-associated transcription factor antibody, microphthalmia-associated transcription factor S homeolog antibody, Microphthalmia antibody, MITF antibody, mitf antibody, LOC100313655 antibody, mitf.S antibody, LOC100534525 antibody, MICROP antibody, Mitf antibody
    背景
    MITF (Microphthalmia-associated transcription factor) is a basic helix-loop-helix leucine zipper (bHLH-Zip) family factor, involved in lineage-specific pathway regulation of many types of cells including osteoclasts, melanocytes, retinal pigment epithelial cells, mast cells and natural killer cells. It plays a critical role in melanogenesis as a transcriptional activator of tyrosinase, TRP-1, and TRP-2. Moreover, it regulates specification, survival, and proliferation of normal melanocytes, and controls proliferation, migration and invasion of melanoma cells. MITF is the most characterized member of the MIT family, mutations of which can lead to diseases such as Melanoma, Waardenburg syndrome, and Tietz syndrome.
    分子量
    30 kDa
    基因ID
    4286
    UniProt
    O75030
    途径
    Chromatin Binding
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