EIF2S3 抗体 (N-Term)
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Quick Overview for EIF2S3 抗体 (N-Term) (ABIN502695)
抗原
See all EIF2S3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AGGEAGVTLG QPHLSRQDLT TLDVTKLTPL SHEVISRQAT INIGTIGHVA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against EIF2S3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EIF2S3
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 472 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EIF2S3 (Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3))
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别名
- EIF2S3
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背景
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EIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Alias Symbols: EIF2, EIF2G, EIF2gamma, eIF-2gA
Protein Interaction Partner: UBC, RNF2, rev, CCAR2, PLD3, EEF1E1, AIMP1, AIP, IQGAP1, RARS, QARS, IMPDH2, DNAJA1, EIF2S1, MAPK6, TARDBP, FN1, UBD, GRK5, CAND1, CDK2, SUMO1, ELAVL1, SUMO2, NDRG1, RAD21, HDGF, DCC, METAP2, EIF1B, CASP4, H3F3A, CTCF,
Protein Size: 472 -
分子量
- 51 kDa
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基因ID
- 1968
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NCBI登录号
- NM_001415, NP_001406
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UniProt
- P41091
抗原
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