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Ectodysplasin A 抗体 (Middle Region)

EDA 适用: 人, 小鼠, 大鼠, Cow, 山羊, 豚鼠, 马, 犬, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN502530
发货至: 中国
  • 抗原 See all Ectodysplasin A (EDA) 抗体
    Ectodysplasin A (EDA)
    抗原表位
    • 16
    • 16
    • 9
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 72
    • 47
    • 28
    • 11
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 山羊, 豚鼠, 马, 犬, 兔, 斑马鱼
    宿主
    • 66
    • 7
    克隆类型
    • 65
    • 7
    • 1
    多克隆
    标记
    • 28
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Ectodysplasin A antibody is un-conjugated
    应用范围
    • 68
    • 37
    • 27
    • 26
    • 26
    • 15
    • 11
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    GPPGPPGPQG PPGLQGPSGA ADKAGTRENQ PAVVHLQGQG SAIQVKNDLS
    预测反应
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against EDA. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human EDA
    Top Product
    Discover our top product EDA Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 389 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zhao, Watt, Battle, Li, Bondow, Duncan: "Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice." in: Developmental biology, Vol. 317, Issue 2, pp. 614-9, (2008) (PubMed).

  • 抗原
    Ectodysplasin A (EDA)
    别名
    EDA (EDA 产品)
    别名
    ECTD1 antibody, ED1 antibody, ED1-A1 antibody, ED1-A2 antibody, EDA-A1 antibody, EDA-A2 antibody, EDA1 antibody, EDA2 antibody, HED antibody, HED1 antibody, ODT1 antibody, STHAGX1 antibody, XHED antibody, XLHED antibody, si:ch73-223d24.5 antibody, Ed1 antibody, Eda-A1 antibody, Eda-A2 antibody, Ta antibody, tabby antibody, RGD1563178 antibody, ectodysplasin A antibody, ectodysplasin-A antibody, EDA antibody, eda antibody, Eda antibody
    背景
    EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. It belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
    Alias Symbols: ED1, ED1-A1, ED1-A2, EDA1, EDA2, HED, XHED, XLHED, ODT1, STHAGX1
    Protein Interaction Partner: OSTCP1, OSTC, NIPAL3, GIMAP5, SEC22A, LEPROTL1, DOLK, PLN, MAL, EMP3, CYB561, ATP6V0C, EDAR, EDA, EDA2R, FURIN,
    Protein Size: 389
    分子量
    41 kDa
    基因ID
    1896
    NCBI登录号
    NM_001005609, NP_001005609
    UniProt
    Q92838
    途径
    Tube Formation
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