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LCLAT1 抗体 (Middle Region)

LCLAT1 适用: 小鼠, 人, 大鼠, 兔, 马, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN502511
发货至: 中国
  • 抗原 See all LCLAT1 抗体
    LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
    抗原表位
    • 15
    • 9
    • 9
    • 6
    • 1
    Middle Region
    适用
    小鼠, 人, 大鼠, 兔, 马, Cow, 犬, 豚鼠
    宿主
    • 33
    克隆类型
    • 33
    多克隆
    标记
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LCLAT1 antibody is un-conjugated
    应用范围
    • 32
    • 15
    • 13
    • 13
    • 12
    • 5
    • 3
    • 1
    Western Blotting (WB)
    序列
    YLYSLVKWYF IITIVIFVLQ ERIFGGLEII ELACYRLLHK QPHLNSKKNE
    预测反应
    Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against LYCAT. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human LYCAT
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 376 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zou, Synan, Li, Xiong, Manni, Liu, Chen, Zhao, Shiva, Tyurina, Jiang, Lee, Das, Ray, Ray, Kagan, Mallampalli: "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1." in: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016) (PubMed).

  • 抗原
    LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
    别名
    LYCAT (LCLAT1 产品)
    别名
    lclat1 antibody, zgc:77380 antibody, wu:fj17g04 antibody, LYCAT antibody, lycat antibody, agpat8 antibody, alcat1 antibody, 1agpat8 antibody, AGPATP8 antibody, 1AGPAT8 antibody, AGPAT8 antibody, ALCAT1 antibody, HSRG1849 antibody, UNQ1849 antibody, AI181996 antibody, Agpat8 antibody, Alcat1 antibody, Gm91 antibody, Lycat antibody, RGD1565906 antibody, lysocardiolipin acyltransferase 1 antibody, lclat1 antibody, LCLAT1 antibody, Lclat1 antibody
    背景
    LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
    Alias Symbols: ALCAT1, FLJ37965, UNQ1849, LYCAT, AGPAT8, 1AGPAT8, HSRG1849
    Protein Interaction Partner: LNX1, GOPC, RNF2, UBC, ELAVL1,
    Protein Size: 376
    分子量
    44 kDa
    基因ID
    253558
    NCBI登录号
    NM_001002257, NP_001002257
    UniProt
    Q6UWP7
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