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MEF2A 抗体 (Middle Region)

MEF2A 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501716
发货至: 中国
  • 抗原 See all MEF2A 抗体
    MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
    抗原表位
    • 20
    • 18
    • 14
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    Middle Region
    适用
    • 125
    • 98
    • 79
    • 10
    • 9
    • 8
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 马, 犬, 兔, 豚鼠
    宿主
    • 122
    • 5
    克隆类型
    • 111
    • 16
    多克隆
    标记
    • 65
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MEF2A antibody is un-conjugated
    应用范围
    • 95
    • 42
    • 40
    • 33
    • 26
    • 26
    • 21
    • 13
    • 6
    • 5
    • 3
    • 2
    • 1
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    • 1
    • 1
    Western Blotting (WB)
    序列
    SLSSSSSSYD GSDREDPRGD FHSPIVLGRP PNTEDRESPS VKRMRMDAWV
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against MEF2A. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MEF2A
    Top Product
    Discover our top product MEF2A Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 507 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
    别名
    MEF2A (MEF2A 产品)
    别名
    ADCAD1 antibody, RSRFC4 antibody, RSRFC9 antibody, mef2 antibody, A430079H05Rik antibody, mef2a antibody, wu:fd19d02 antibody, adcad1 antibody, rsrfc4 antibody, rsrfc9 antibody, sl2 antibody, MEF2A antibody, xmef2a antibody, myocyte enhancer factor 2A antibody, myocyte enhancer factor 2aa antibody, myocyte enhancer factor 2a antibody, myocyte-specific enhancer factor 2A antibody, myocyte-specific enhancer factor 2a, putative antibody, myocyte enhancer factor 2A L homeolog antibody, MEF2A antibody, Mef2a antibody, mef2aa antibody, EDI_092490 antibody, EDI_038250 antibody, Smp_161530 antibody, mef2a.L antibody, mef2a antibody, LOC539054 antibody
    背景
    The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ADCAD1, RSRFC4, RSRFC9, mef2
    Protein Interaction Partner: HDAC7, HDAC5, HDAC3, TAF8, GNG12, TBP, GNB2, ERBB2IP, NDUFB9, DDB1, Dlg4, PHB2, ASCL1, SUMO1, UBE2I, SUMO2, HNRNPA1, UBC, MEF2D, HDAC1, EP300, HDAC4, ACTN4, THRA, HDAC9, MAPK7, CASP7, SMAD2, SMAD4, MEF2A, CASP3, MAPK14, TEAD1, MYOG, MYOD1, CDK5, VGLL4,
    Protein Size: 507
    分子量
    55 kDa
    基因ID
    4205
    NCBI登录号
    NM_005587, NP_005578
    UniProt
    Q02078
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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