(1 reference)-
- 抗原 See all FGD1 抗体
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
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抗原表位
- N-Term
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适用
- 人, Cow, Pig, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FGD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- HGHRAPGGAG PSEPEHPATN PPGAAPPACA DSDPGASEPG LLARRGSGSA
- 预测反应
- Cow: 86%, Human: 100%, Pig: 86%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against FGD1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FGD1
- Top Product
- Discover our top product FGD1 Primary Antibody
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anti-FYVE, RhoGEF and PH Domain Containing 1 (FGD1) (AA 700-800) antibody
FGD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FYVE, RhoGEF and PH Domain Containing 1 (FGD1) (C-Term) antibodyFGD1 适用: 人, Cow, 犬, Pig, 大鼠, 小鼠, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FYVE, RhoGEF and PH Domain Containing 1 (FGD1) (N-Term) antibodyFGD1 适用: 人, Cow, 犬, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-FYVE, RhoGEF and PH Domain Containing 1 (FGD1) (C-Term) antibodyFGD1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FYVE, RhoGEF and PH Domain Containing 1 (FGD1) (N-Term) antibodyFGD1 适用: 人, Cow, Pig, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-FYVE, RhoGEF and PH Domain Containing 1 (FGD1) antibodyFGD1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 961 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice." in: The Journal of clinical investigation, Vol. 121, Issue 11, pp. 4383-92, (2011) (PubMed).
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: "MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice." in: The Journal of clinical investigation, Vol. 121, Issue 11, pp. 4383-92, (2011) (PubMed).
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- 抗原
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
- 别名
- FGD1 (FGD1 产品)
- 别名
- AAS antibody, FGDY antibody, MRXS16 antibody, ZFYVE3 antibody, FYVE, RhoGEF and PH domain containing 1 antibody, FGD1 antibody, Fgd1 antibody, fgd1 antibody
- 背景
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FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AAS, FGDY, ZFYVE3, MRXS16
Protein Interaction Partner: BTRC, UBC, ELAVL1, ELMO1, CTTN, CDC42, AOC1,
Protein Size: 961 - 分子量
- 106 kDa
- 基因ID
- 2245
- NCBI登录号
- NM_004463, NP_004454
- UniProt
- P98174
- 途径
- Neurotrophin Signaling Pathway
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