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STAT5A 抗体 (C-Term)

Name: STAT5A 抗体 (C-Term)
SKU: ABIN501656
Availability: OutOfStock

STAT5A 适用: 人, 小鼠, 大鼠, Cow, 绵羊, Pig, 犬, 马, 兔, 山羊, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-STAT5A Antibody Titration: 0.

Rabbit Anti-STAT5A Antibody Formalin Fixed Paraffin Embedded Tissue: Human Bone Marrow Tissue Observed Staining: Cytoplasm, Nucleus Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.

IHC

2 images

(1 reference)

产品编号 ABIN501656

发货至: 中国

Datasheet as PDF

抗原 See all STAT5A 抗体

STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
抗原表位
46

24

17

15

15

14

9

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
190

101

75

25

9

8

7

6

4

3

3

1

1

1

1
人, 小鼠, 大鼠, Cow, 绵羊, Pig, 犬, 马, 兔, 山羊, 豚鼠
宿主
175

18

2
兔
Compatible Secondaries
克隆类型
156

39
多克隆
标记
113

10

7

6

6

6

6

6

6

5

4

3

3

3

3

3

3

1

1
This STAT5A antibody is un-conjugated
应用范围
158

69

56

40

39

30

23

21

19

13

10

8

6

5

3

2

2

1

1

1

1
Western Blotting (WB)

序列

DQAPSPAVCP QAPYNMYPQN PDHVLDQDGE FDLDETMDVA RHVEELLRRP

预测反应

Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 86%, Rat: 92%, Sheep: 93%

产品特性

This is a rabbit polyclonal antibody against STAT5A. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human STAT5A

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Discover our top product STAT5A Primary Antibody
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 6E5 unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 583-794) antibody
STAT5A 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6D4 unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-794) antibody
STAT5A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-104) antibody
STAT5A 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1B12 unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 635-794) antibody
STAT5A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (C-Term) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pTyr694) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pSer780) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 61-160) antibody
STAT5A 适用: 人, 小鼠, 大鼠, Cow WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 763-797), (C-Term) antibody
STAT5A 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52392 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 794 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Murayama, Ohmori, Fujimura, Minami, Yasuzawa-Tanaka, Kuroda, Oie, Daitoku, Okuwaki, Nagata, Fukamizu, Kimura, Shimizu, Yanagisawa: "Epigenetic control of rDNA loci in response to intracellular energy status." in: Cell, Vol. 133, Issue 4, pp. 627-39, (2008) (PubMed).
抗原

STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))

别名

STAT5A (STAT5A 产品)

别名

MGF antibody, STAT5 antibody, AA959963 antibody, Stat5 antibody, STAT5A/MGF antibody, STATA5 antibody, STAT5A antibody, stat5 antibody, stat5b antibody, signal transducer and activator of transcription 5A antibody, signal transducer and activator of transcription 5a antibody, STAT5A antibody, Stat5a antibody, stat5a antibody, LOC100348518 antibody, LOC100716811 antibody

背景

STAT5A is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGF, STAT5
Protein Interaction Partner: TCF12, NLK, LEF1, NARF, CBL, UBC, ESR1, HELZ, UGT2B4, STAT5A, POM121C, WASH2P, AQP11, ZNF596, MRPS6, TXNDC11, RBMX, INSR, GLUD1, FN1, EPAS1, CYP2C9, CSNK2B, JAK2, BTK, EPOR, CRKL, SOCS7, NFKB1, ERBB4, EP300, MYB, SQSTM1, GNB2, SMARCA4, PGR, FGFR2, JAK3, C
Protein Size: 794

分子量

91 kDa

基因ID

6776

NCBI登录号

NM_003152, NP_003143

UniProt

P42229

途径

JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation