电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PSMC2 抗体 (N-Term)

PSMC2 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 山羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501257
发货至: 中国
  • 抗原 See all PSMC2 抗体
    PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))
    抗原表位
    • 15
    • 13
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 40
    • 34
    • 32
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 山羊
    宿主
    • 47
    • 8
    克隆类型
    • 47
    • 7
    多克隆
    标记
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMC2 antibody is un-conjugated
    应用范围
    • 47
    • 23
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    MPDYLGADQR KTKEDEKDDK PIRALDEGDI ALLKTYGQST YSRQIKQVED
    预测反应
    Cow: 100%, Dog: 100%, Goat: 77%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against PSMC2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PSMC2
    Top Product
    Discover our top product PSMC2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 433 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))
    别名
    PSMC2 (PSMC2 产品)
    别名
    xMSS1 antibody, psmc2 antibody, DDBDRAFT_0168337 antibody, DDBDRAFT_0232966 antibody, DDB_0168337 antibody, DDB_0232966 antibody, MSS1 antibody, Nbla10058 antibody, S7 antibody, NCU02840.1 antibody, zgc:63995 antibody, proteasome 26S subunit, ATPase 2 L homeolog antibody, proteasome (prosome, macropain) 26S subunit, ATPase 2 antibody, 26S protease regulatory subunit 7 antibody, proteasome 26S subunit, ATPase 2 antibody, regulatory particle, ATPase-like-1 antibody, psmc2.L antibody, psmc2 antibody, psmC2 antibody, PSMC2 antibody, rpt-1 antibody, GL50803_21331 antibody, EHI_080890 antibody, UREG_01412 antibody, PITG_10169 antibody, Psmc2 antibody, GL50803_86683 antibody, Tsp_09237 antibody
    背景
    The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, PSMC2 is a positive modulator of Tat-mediated transactivation.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC3004, MSS1, Nbla10058, S7
    Protein Interaction Partner: HUWE1, UBC, PSMD5, SPRTN, SUMO2, SHFM1, PSMD14, PSMD4, RNF2, PSMC1, CLIP1, RPS21, PSMD12, PSMD11, PSMD8, PSMD3, PSMD2, PSMD1, PSMC6, PSMC3, ADRM1, TXNL1, FBXO6, PARK2, BAG3, NOS2, SKIL, RAD23A, PCDH10, UCHL5, PSMD6, PSMD13, PSMD7, PSMC4, ZCCHC8, UFC1, MRP
    Protein Size: 433
    分子量
    49 kDa
    基因ID
    5701
    NCBI登录号
    NM_002803, NP_002794
    UniProt
    P35998
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
You are here:
客服