DIABLO 抗体 (C-Term)
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- 抗原 See all DIABLO 抗体
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
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抗原表位
- AA 222-237, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DIABLO antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects DIABLO / SMAC at C-term.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- Smac antibody was raised against a peptide corresponding to amino acids 222 to 237 of murine Smac/DIABLO.
- 亚型
- IgG
- Top Product
- Discover our top product DIABLO Primary Antibody
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anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 211-239), (C-Term) antibody
DIABLO 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20755 unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-232) antibodyDIABLO 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 131-239) antibodyDIABLO 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibodyDIABLO 适用: 人, 猴 WB, IHC (p) 宿主: 小鼠 Monoclonal 79-1-83 unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 56-239) antibodyDIABLO 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 225-239) antibodyDIABLO 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 222-237) antibodyDIABLO 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibodyDIABLO 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 168-236) antibodyDIABLO 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-239) antibodyDIABLO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot: 0.5 to 1 μg/mL, 25 kDa band can be detected. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
- 别名
- DIABLO / SMAC (DIABLO 产品)
- 别名
- smac antibody, smac3 antibody, diablo-s antibody, 0610041G12Rik antibody, 1700006L01Rik antibody, AU040403 antibody, Smac antibody, DFNA64 antibody, SMAC antibody, DBO antibody, XSmac antibody, diablo, IAP-binding mitochondrial protein antibody, diablo IAP-binding mitochondrial protein antibody, diablo, IAP-binding mitochondrial protein L homeolog antibody, diablo antibody, Diablo antibody, DIABLO antibody, diablo.L antibody
- 背景
- The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes. A novel mammalian protein that binds to IAPs and neutralizes the inhibitory effect of IAPs on caspases was recently identified and designated Smac/DIABLO (1,2). Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/capase-9 pathway. Analysis of the structural basis of Smac/DIABLO reveals that the N-terminal amino acids are required for binding of Smac/DIABLO to IAPs and activation of caspases (3-6). Smac/DIABLO is expressed in a variety of human and mouse tissues (1,2).Synonyms: Diablo homolog mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase
- 基因ID
- 66593
- UniProt
- Q9JIQ3
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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