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RIPK3 抗体 (AA 473-486)

RIPK3 适用: 小鼠, 大鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500612
发货至: 中国
  • 抗原 See all RIPK3 抗体
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    抗原表位
    • 11
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 473-486
    适用
    • 80
    • 40
    • 18
    • 6
    • 4
    • 4
    • 2
    • 1
    小鼠, 大鼠
    宿主
    • 80
    • 9
    克隆类型
    • 80
    • 9
    多克隆
    标记
    • 44
    • 9
    • 8
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RIPK3 antibody is un-conjugated
    应用范围
    • 82
    • 52
    • 44
    • 18
    • 11
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects RIP3.
    交叉反应 (详细)
    Species reactivity (tested):Mouse, Rat.
    纯化方法
    Peptide Affinity Chromatography
    免疫原
    RIP3 antibody was raised against a peptide corresponding to amino acids 473 to 486 of Murine RIP3.
    亚型
    IgG
    Top Product
    Discover our top product RIPK3 Primary Antibody
  • 应用备注
    ELISA. Western blot: 0.5 to 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    别名
    RIPK3 / RIP3 (RIPK3 产品)
    别名
    RIPK3 antibody, RIP3 antibody, 2610528K09Rik antibody, AW107945 antibody, Rip3 antibody, Hcyp2 antibody, receptor interacting serine/threonine kinase 3 antibody, receptor interacting serine/threonine kinase 3 S homeolog antibody, receptor-interacting serine-threonine kinase 3 antibody, RIPK3 antibody, ripk3.S antibody, Ripk3 antibody
    背景
    Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3 (1-3). RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-kB activation. Overexpression of RIP3 induces apoptosis and NF-kappaB activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues (2,3).Synonyms: RIP-3, RIP-like protein kinase 3, Receptor-interacting protein 3, Receptor-interacting serine/threonine-protein kinase 3
    分子量
    57 kDa
    基因ID
    56532
    UniProt
    Q9QZL0
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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