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RIPK2 抗体 (N-Term)

RIPK2 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500599
发货至: 中国
  • 抗原 See all RIPK2 抗体
    RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
    抗原表位
    • 12
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 68
    • 36
    • 18
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 63
    • 6
    • 1
    克隆类型
    • 65
    • 5
    多克隆
    标记
    • 40
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RIPK2 antibody is un-conjugated
    应用范围
    • 53
    • 34
    • 25
    • 10
    • 9
    • 7
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects RICK at N-term.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    RICK antibody was raised against a peptide corresponding to amino acids near the amino terminus of human RICK.
    亚型
    IgG
    Top Product
    Discover our top product RIPK2 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1: 1000, an approximately 60 kDa band can be detected. Immuoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
    别名
    RIPK2 (RIPK2 产品)
    别名
    RIPK2 antibody, 2210420D18Rik antibody, CARD3 antibody, CARDIAK antibody, CCK antibody, D4Bwg0615e antibody, RICK antibody, RIP2 antibody, GIG30 antibody, receptor interacting serine/threonine kinase 2 antibody, receptor (TNFRSF)-interacting serine-threonine kinase 2 antibody, receptor-interacting serine-threonine kinase 2 antibody, RIPK2 antibody, Ripk2 antibody
    背景
    Apoptosis is mediated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. DD-containing serine/threonine kinase RIP regulates Fas-induced apoptosis. A novel CARD-containing serine/threonine kinase was recently identified and designated RICK/RIP2/CARDIAK for RIP-like interacting CLARP kinase, receptor interacting protein-2, and CARD-containing ICE associated kinase, respectively, (1-3). RICK contains an N-terminal kinase catalytic domain and a C-terminal CARD domain. Overexpression of RICK induced apoptosis and activation of NF-kappaB and JNK. RICK interacts with members of the TRAF family, CLARP and caspase-1. Thus, RICK represents a novel kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1b. The messenger RNA of RICK is expressed in multiple human tissues.Synonyms: CARD-containing IL-1 beta ICE-kinase, CARDIAK, RICK, RIP-2, RIP-like-interacting CLARP kinase, RIP2, Receptor-interacting protein 2, Receptor-interacting serine/threonine-protein kinase 2
    基因ID
    8767
    UniProt
    O43353
    途径
    TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades
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