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Neurturin 抗体 (AA 178-193)

NRTN 适用: 人 WB, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500336
发货至: 中国
  • 抗原 See all Neurturin (NRTN) 抗体
    Neurturin (NRTN)
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    AA 178-193
    适用
    • 47
    • 21
    • 16
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 42
    • 3
    • 2
    • 2
    克隆类型
    • 46
    • 3
    多克隆
    标记
    • 23
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Neurturin antibody is un-conjugated
    应用范围
    • 47
    • 26
    • 13
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects Neurturin.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Peptide affinity chromatography
    免疫原
    Neurturin antibody was raised against a peptide corresponding to amino acids 178 to 193 of human neurturin.
    亚型
    IgG
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    Discover our top product NRTN Primary Antibody
  • 应用备注
    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Neurturin (NRTN)
    别名
    Neurturin (NRTN 产品)
    别名
    NRTN antibody, NTN antibody, neurturin antibody, NRTN antibody, Nrtn antibody
    背景
    Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation. A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin. Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently (3-8) and termed GDNFRb, Ret ligand 2 (RETL2) or TGF-Β-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRalpha-2 recently. NTN binds to and forms a complex with GFRalpha-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway. Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations. Neurturin and GDNF define a new family of neurotrophic factors.Synonyms: NRTN
    基因ID
    4902
    NCBI登录号
    NP_004549
    UniProt
    Q99748
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