-
- 抗原 See all TBK1 抗体
- TBK1 (TANK-Binding Kinase 1 (TBK1))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This TBK1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects TBK1 at C-term. It has no cross response to IKKa, IKKb, IKKy, or IKKe.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- Peptide from C-term of human NAK / TBK1 (Cat. No. 2351P)
- 亚型
- IgG
- Top Product
- Discover our top product TBK1 Primary Antibody
-
anti-TANK-Binding Kinase 1 (TBK1) (AA 440-729) antibody
TBK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) antibodyTBK1 适用: 人 WB, IP, IF 宿主: 兔 Monoclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (pSer172) antibodyTBK1 适用: 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 9-310) antibodyTBK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 150-181) antibodyTBK1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB16573 unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 364-585) antibodyTBK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (C-Term) antibodyTBK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 563-577) antibodyTBK1 适用: 人 WB 宿主: 小鼠 Monoclonal 108A429 unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 644-661) antibodyTBK1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 74-123) antibodyTBK1 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, Pig, 兔, 马, 豚鼠, 斑马鱼, Hamster, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA. Western blot: 0.5 - 1 μg/mL, an 84 kDa band should be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- TBK1 (TANK-Binding Kinase 1 (TBK1))
- 别名
- TBK1 (TBK1 产品)
- 别名
- nak antibody, t2k antibody, TBK1 antibody, wu:fk70c05 antibody, zgc:136548 antibody, NAK antibody, T2K antibody, 1200008B05Rik antibody, AI462036 antibody, AW048562 antibody, TANK binding kinase 1 L homeolog antibody, TANK binding kinase 1 antibody, TANK-binding kinase 1 antibody, tbk1.L antibody, TBK1 antibody, tbk1 antibody, Tbk1 antibody
- 背景
- Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kappaB is associated with IkappaB proteins in the cell cytoplasm, which inhibit NF-kappaB activity. Phosphorylation of I-kappaB by IkappaB kinase (IKK) complex leads to degradation of I-kappaB and activation of NF-kappaB. The IKK complex contains IKKalpha, IKKbeta, and IKKgamma. A novel IKK related kinase was recently identified and designated TBK1 (TANK-binding kinase 1), NAK (NF-kappaB-activating kinase), and T2K (1-3). NAK/TBK1 activates IKKbeta through direct phosphorylation. NAK/TBK1 is activated by growth factors and PMA and mediates IKK and NF-kappaB activation in response to growth factors (2). NAK/TBK1 functions upstream of NIK and the IKK complex (1,2). NAK/TBK1 is also critical in protecting embryonic liver from apoptosis (3).Synonyms: NAK, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1
- 基因ID
- 29110
- NCBI登录号
- NP_037386
- UniProt
- Q9UHD2
- 途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
-
You are here:
