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IRAK1 抗体 (C-Term)

IRAK1 适用: 人, 小鼠, 大鼠 WB, IP, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500036
发货至: 中国
  • 抗原 See all IRAK1 抗体
    IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
    抗原表位
    • 31
    • 19
    • 18
    • 16
    • 10
    • 8
    • 8
    • 6
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    • 2
    • 2
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    C-Term
    适用
    • 142
    • 85
    • 61
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 141
    • 13
    • 2
    克隆类型
    • 144
    • 12
    多克隆
    标记
    • 62
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
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    • 5
    • 3
    This IRAK1 antibody is un-conjugated
    应用范围
    • 113
    • 69
    • 65
    • 55
    • 52
    • 25
    • 17
    • 14
    • 13
    • 11
    • 8
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    IRAK antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human IRAK.
    纯化方法
    DEAE
    免疫原
    Human IRAK (C-Terminus) Peptide
    亚型
    IgG
    Top Product
    Discover our top product IRAK1 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1/1000. Immunocytochemistry. Immunoprecipitation: 2 to 4 μg per sample. An 80 kDa band should be detected in the lysate from non-activated cells. It has no crossresponse to IRAK2.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
    别名
    IRAK1 (IRAK1 产品)
    别名
    IRAK1 antibody, IRAK antibody, pelle antibody, AA408924 antibody, IRAK-1 antibody, IRAK1-S antibody, Il1rak antibody, Plpk antibody, mPLK antibody, RGD1563841 antibody, interleukin 1 receptor associated kinase 1 antibody, interleukin-1 receptor-associated kinase 1 antibody, IRAK1 antibody, irak1 antibody, Irak1 antibody
    背景
    Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-kappaB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).Synonyms: IRAK, IRAK-1, Interleukin-1 receptor-associated kinase 1
    基因ID
    3654
    UniProt
    P51617
    途径
    NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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