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IL27 抗体 (N-Term)

IL27 适用: 人, 小鼠 WB, EIA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500000
发货至: 中国
  • 抗原 See all IL27 抗体
    IL27 (Interleukin-27 Subunit alpha (IL27))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 16
    • 13
    • 10
    人, 小鼠
    宿主
    • 15
    • 4
    克隆类型
    • 15
    • 4
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL27 antibody is un-conjugated
    应用范围
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
    特异性
    This antibody reacts to IL-27.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Affinity chromatography purified via peptide column
    亚型
    IgG
    Top Product
    Discover our top product IL27 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 2 - 4 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    IL27 (Interleukin-27 Subunit alpha (IL27))
    别名
    Interleukin-27 / IL27A (IL27 产品)
    背景
    Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-γ, and T-bet.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28
    基因ID
    246778
    NCBI登录号
    NP_663634
    UniProt
    Q8NEV9
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