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TNFSF18 抗体

TNFSF18 适用: 人, 小鼠 WB, EIA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499890
发货至: 中国
  • 抗原 See all TNFSF18 抗体
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    适用
    • 60
    • 29
    • 6
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 51
    • 10
    • 6
    克隆类型
    • 50
    • 15
    • 1
    多克隆
    标记
    • 34
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    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This TNFSF18 antibody is un-conjugated
    应用范围
    • 53
    • 32
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
    特异性
    GITRL antibody was raised against purified recombinant human GITR ligand.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Recombinant human GITR ligand
    亚型
    IgG
    Top Product
    Discover our top product TNFSF18 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    别名
    TNFSF18 / AITRL (TNFSF18 产品)
    别名
    Gitrl antibody, AITRL antibody, GITRL antibody, TL6 antibody, hGITRL antibody, TNLG2A antibody, tumor necrosis factor (ligand) superfamily, member 18 antibody, TNF superfamily member 18 antibody, Tnfsf18 antibody, TNFSF18 antibody
    背景
    The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-kappaB and various mitogen-activated protein kinases (reviewed in 1). The glucocorticoid-induced tumor necrosis factor receptor (GITR) is an emerging member of this family that is expressed on CD4+ CD25+ regulatory T cells and appears to have crucial immune regulation functions (2,3). Its ligand GITRL is expressed in endothelial and antigen-presenting cells (4) and can activate NF-kappaB, induce both pro- and anti-apoptotic effects, inhibit the suppressive activity of regulatory T cells, and co-stimulate responder T cells through GITR (5). Dominant negative forms of NIK and TRAF2 expressed in transfected 293 cells substantially inhibited NF-kappaB activation, suggesting that the GITRL-GITR pathway involves both NIK and TRAF2 (4).Synonyms: AITRL, Activation-inducible TNF-related ligand, GITRL, Glucocorticoid-induced TNF-related ligand, TL6, Tumor necrosis factor ligand superfamily member 18, hGITRL
    基因ID
    8995
    UniProt
    Q9UNG2
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