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- 抗原 See all TNFRSF12A 抗体
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFRSF12A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to Fn14.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Fn14 antibody was raised against a human IgG1 Fc-tagged Fn14 protein.
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF12A Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-80) antibody
TNFRSF12A 适用: 人 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 5C9B4 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 24-126) antibodyTNFRSF12A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) antibodyTNFRSF12A 适用: 人, 小鼠 WB, FACS, IHC (fro), Func 宿主: 小鼠 Monoclonal ITEM-4 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) antibodyTNFRSF12A 适用: 人, 小鼠 WB, FACS, IHC (fro) 宿主: 小鼠 Monoclonal ITEM-4 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) antibodyTNFRSF12A 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 7H8 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 104-118) antibodyTNFRSF12A 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 104-118) antibodyTNFRSF12A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) antibody (PE)TNFRSF12A 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal ITEM-4 PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-129) antibodyTNFRSF12A 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1B6 unconjugated
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- 应用备注
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ELISA. Western BLot: 2-4 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
- 别名
- CD266 / TweakR (TNFRSF12A 产品)
- 别名
- CD266 antibody, FN14 antibody, TWEAKR antibody, AI255180 antibody, C87282 antibody, Fn14 antibody, HPIP antibody, TWEAK-R antibody, TweakR antibody, TNF receptor superfamily member 12A antibody, tumor necrosis factor receptor superfamily, member 12a antibody, TNFRSF12A antibody, Tnfrsf12a antibody
- 背景
- TWEAK is a TNF family member produced by IFN-gamma-stimulated monocytes and induces multiple cell death pathways including caspase-dependent apoptosis and cathepsin B-dependent necrosis. These pathways are mediated by the binding of TWEAK by fibroblast growth factor 14 (Fn14), a member of the TNF receptor superfamily. Yeast two-hybrid experiments have shown that FN14 will bind to the TNFR-associated factors TRAF1, TRAF2, TRAF3, and TRAF5, suggesting that the signaling pathway induced by TWEAK may be mediated by one or more of these adaptor molecules. Fn14 is induced during liver regeneration and is highly expressed in hepatocellular carcinomas. In addition, TWEAK induces liver progenitor cell proliferation, suggesting Fn14 may play a role in hepatocyte growth control and liver neoplasia.Synonyms: FGF-inducible 14, FN14, Fibroblast growth factor-inducible immediate-early response protein 14, TNFRSF12A, Tumor necrosis factor receptor superfamily member 12A, Tweak receptor
- 基因ID
- 51330
- NCBI登录号
- NP_057723
- UniProt
- Q9NP84
- 途径
- Apoptosis, Regulation of Cell Size
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