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- 抗原 See all FLASH (CASP8AP2) 抗体
- FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FLASH antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- FLASH antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy-terminus of human FLASH which differ from those of mouse by one amino acid.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Human FLASH (C-Terminus) Peptide
- 亚型
- IgG
- Top Product
- Discover our top product CASP8AP2 Primary Antibody
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anti-CASP8 Associated Protein 2 (CASP8AP2) antibody
CASP8AP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CASP8 Associated Protein 2 (CASP8AP2) (AA 110-159) antibodyCASP8AP2 适用: 人, 小鼠, 大鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-CASP8 Associated Protein 2 (CASP8AP2) (AA 1733-1982) antibodyCASP8AP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CASP8 Associated Protein 2 (CASP8AP2) (N-Term) antibodyCASP8AP2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-CASP8 Associated Protein 2 (CASP8AP2) antibodyCASP8AP2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: 0.25 to 0.5 μg/mL. An approximate 220 kDa band can be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
- 别名
- CASP8AP2 / FLASH (CASP8AP2 产品)
- 别名
- CASP8AP2 antibody, FLASH antibody, fc74h10 antibody, wu:fc74h10 antibody, zgc:113449 antibody, CED-4 antibody, RIP25 antibody, AA387232 antibody, D4Ertd659e antibody, mKIAA1315 antibody, caspase 8 associated protein 2 antibody, CASP8AP2 antibody, casp8ap2 antibody, Casp8ap2 antibody
- 背景
- A novel mammalian CED-4 homologous was recently identified and cloned in mouse (1) and human (2) and designated FLASH (for FLICE-associated huge protein). FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8 (1). There are parallels between FLASH and Apaf-1/CED-4 although there are arguments against their structural similarity (1,2). FLASH is widely expressed.Synonyms: CASP8-associated protein 2, KIAA1315, RIP25
- 基因ID
- 9994
- UniProt
- Q9Y563
- 途径
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
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