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DR3/LARD 抗体 (Extracellular Domain)

TNFRSF25 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499758
发货至: 中国
  • 抗原 See all DR3/LARD (TNFRSF25) 抗体
    DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
    抗原表位
    • 15
    • 15
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
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    • 2
    • 2
    • 2
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    • 1
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    • 1
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    • 1
    • 1
    Extracellular Domain
    适用
    • 81
    • 27
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 73
    • 10
    克隆类型
    • 72
    • 10
    多克隆
    标记
    • 39
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DR3/LARD antibody is un-conjugated
    应用范围
    • 72
    • 35
    • 26
    • 26
    • 9
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    Recognizes TNFRSF25.
    纯化方法
    DEAE-Column Chromatography.
    免疫原
    Synthetic peptide corresponding to amino acids in extracellular domain (ED) of Human DR3 precusor.
    亚型
    IgG
    Top Product
    Discover our top product TNFRSF25 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1/500 to 1/1000.59 kDa band should be detected. Immuocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
    别名
    TNFRSF25 / DR3 / TRAMP (TNFRSF25 产品)
    别名
    APO-3 antibody, DDR3 antibody, DR3 antibody, LARD antibody, TNFRSF12 antibody, TR3 antibody, TRAMP antibody, WSL-1 antibody, WSL-LR antibody, Tnfrsf12 antibody, Wsl antibody, TNFRSF25 antibody, TNF receptor superfamily member 25 antibody, tumor necrosis factor receptor superfamily, member 25 antibody, TNFRSF25 antibody, Tnfrsf25 antibody
    背景
    Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kappaB activation.Synonyms: AIR, APO3, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, DDR3, Death receptor 3, LARD, Lymphocyte-associated receptor of death, Protein WSL, Protein WSL-1, TNFRSF12, Tumor necrosis factor receptor superfamily member 25, WSL, WSL1
    基因ID
    8718
    UniProt
    Q93038
    途径
    Apoptosis
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