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CCR3 抗体 (C-Term)

CCR3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499597
发货至: 中国
  • 抗原 See all CCR3 抗体
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    抗原表位
    • 15
    • 8
    • 8
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 74
    • 30
    • 23
    • 4
    人, 小鼠, 大鼠
    宿主
    • 53
    • 14
    • 6
    • 5
    克隆类型
    • 57
    • 20
    • 1
    多克隆
    标记
    • 40
    • 8
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR3 antibody is un-conjugated
    应用范围
    • 50
    • 26
    • 26
    • 19
    • 15
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    CCR3 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human CCR3.
    纯化方法
    Immunoaffinity
    免疫原
    Human CCR3 (C-Terminus) Peptide
    亚型
    IgG
    Top Product
    Discover our top product CCR3 Primary Antibody
  • 应用备注
    ELISA. Western Blot: CCR3 antibody can be used for the detection of CCR3 at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    别名
    CD193 / CCR3 (CCR3 产品)
    背景
    Human immunodeficiency virus (HIV) and related virus require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b, CCR8, GPR15, STRL33, and CX3CR1 in the chemokine receptor family were recently identified as HIV coreceptors. CCR5, CXCR4 and CCR3 are the principal receptors for HIV fusion and entry of target cells. CCR3 facilitates infection by a subset of virus. CCR3 and CCR5 promote efficient infection of microglia, the major target cells in the CNS (3,4). High levels of CCR3 and CXCR4 expression were found on the neurons from both the central and peripheral nervous systems. The CCR3 ligand, eotaxin, and an anti-CCR3 antibody inhibited HIV infection of microglia. These results indicate CCR3 plays an important role in HIV infection of CNS.Synonyms: C-C CKR-3, C-C chemokine receptor type 3, CC-CKR-3, CCR-3, CKR3, CMKBR3, Eosinophil eotaxin receptor
    基因ID
    1232
    NCBI登录号
    NP_847899
    UniProt
    P51677
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