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Caspase 9 抗体 (Intermediate Domain 2)

CASP9 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499579
发货至: 中国
  • 抗原 See all Caspase 9 (CASP9) 抗体
    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
    抗原表位
    • 24
    • 16
    • 16
    • 16
    • 16
    • 11
    • 6
    • 5
    • 5
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    Intermediate Domain 2
    适用
    • 218
    • 132
    • 112
    • 19
    • 18
    • 16
    • 10
    • 1
    • 1
    • 1
    • 1
    宿主
    • 212
    • 17
    克隆类型
    • 198
    • 31
    多克隆
    标记
    • 129
    • 11
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    • 7
    • 5
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    This Caspase 9 antibody is un-conjugated
    应用范围
    • 212
    • 81
    • 67
    • 67
    • 62
    • 53
    • 43
    • 40
    • 24
    • 18
    • 18
    • 5
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    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    Caspase-9 antibody was raised against a peptide corresponding to amino acids 299 to 318 of human caspase-9. It has no cross response to other members in caspase family.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Human Caspase-9 (Intermediate Domain 2) Peptide
    亚型
    IgG
    Top Product
    Discover our top product CASP9 Primary Antibody
  • 应用备注
    ELISA. Western Blot: Caspase-9 antibody can be used for detection of caspase-9 at 1/1000 to1/2000 dilution. A 46 kDa band should be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
    别名
    Caspase-9 (CASP9 产品)
    别名
    CASP9 antibody, AI115399 antibody, APAF-3 antibody, AW493809 antibody, CASP-9 antibody, Caspase-9 antibody, ICE-LAP6 antibody, Mch6 antibody, Apaf3 antibody, Casp-9-CTD antibody, Casp9_v1 antibody, Ice-Lap6 antibody, APAF3 antibody, MCH6 antibody, PPP1R56 antibody, caspase 9 antibody, CASP9 antibody, Casp9 antibody
    背景
    Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3 (1-3). Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation (3). Caspase-9 is also activated by granzyme B and CPP32 (1,2). Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis (3). Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFalpha, TRAIL, anti-CD-95, FADD, and TRADD (4). Caspase-9 is expressed in a variety of human tissues (1,2).Synonyms: APAF-3, APAF3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, ICE-LAP6, ICE-like apoptotic protease 6, MCH6
    基因ID
    842
    UniProt
    P55211
    途径
    MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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