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- 抗原 See all BIK 抗体
- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BIK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- This anitbody reacts to BIK.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- BIK antibody was raised against a 15 amino acid peptide from near the amino terminus of human BIK.
- 亚型
- IgG
- Top Product
- Discover our top product BIK Primary Antibody
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anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) antibody
BIK 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 1-123) antibodyBIK 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 37-136) antibodyBIK 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G12 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibodyBIK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibodyBIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 1-123) antibodyBIK 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 39-74) antibodyBIK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3381 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibodyBIK 适用: 人, 小鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: BIK antibody can be used for the detection of BIK ot at 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
- 别名
- BIK (BIK 产品)
- 别名
- BIK antibody, Biklk antibody, Blk antibody, Nbk antibody, BIP1 antibody, BP4 antibody, NBK antibody, si:dkey-31f5.6 antibody, BCL2 interacting killer antibody, BCL2-interacting killer antibody, BCL2-interacting killer (apoptosis-inducing) antibody, BIK antibody, Bik antibody, bik antibody
- 背景
- Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by the activation of proteolytic enzymes termed caspases. Proteins that comprise the Bcl-2 family appear to control the activation of these enzymes. One such protein BIK was recently identified as an endoplasmic reticulum (ER)-residing pro-apoptotic member of the Bcl-2 homology domain-3 (BH3)-only group of the Bcl-2 family that stimulates mitochondrial release of cytochrome c following p53 induction of apoptosis. A significant fraction of BIK is found as an ER transmembrane protein, with most of the protein facing the cytosol. Restricting BIK to the ER membrane by replacing the transmembrane region with that of the ER-selective membrane anchor of cytochrome b(5) resulted in a decreased cytochrome c release from mitochondria and a corresponding drop in cell death. Recent evidence suggests that BIK cooperates with NOXA, another BH3-only protein, to somehow enhance the activation of Bax to stimulate the rapid release of cytochrome c from mitochondria.Synonyms: Apoptosis inducer NBK, BIP1, BP4, Bcl-2-interacting killer, NBK
- 基因ID
- 638
- UniProt
- Q13323
- 途径
- Positive Regulation of Endopeptidase Activity
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