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- 抗原 See all ANTXR1 抗体
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ANTXR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- ATR antibody was raised against a peptide corresponding to 13 amino acids near the C-terminus of human ATR. ATR will recognize only the largest isoform.
- 纯化方法
- Ion exchange chromatography
- 免疫原
- Human ATR / TEM8 (C-Terminus) Peptide
- 亚型
- IgG
- Top Product
- Discover our top product ANTXR1 Primary Antibody
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anti-anthrax Toxin Receptor 1 (ANTXR1) (Tyr382) antibody
ANTXR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (pTyr382) antibodyANTXR1 适用: 人 ELISA, DB 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (C-Term) antibodyVerified ANTXR1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (Internal Region) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (Internal Region) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 481-497) antibodyANTXR1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 200C1339(SB20) unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 315-564) antibodyANTXR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) antibodyANTXR1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 481-497) antibodyANTXR1 适用: 人, 犬, 兔, 猴 WB 宿主: 小鼠 Monoclonal 200C1339(SB20) unconjugated
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- 应用备注
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ELISA. Western Blot: ATR antibody can be used for detection of ATR by Western blot at 1 to 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- 别名
- Anthrax Toxin Receptor 1 (ANTXR1 产品)
- 别名
- ANTXR1 antibody, ATR antibody, TEM8 antibody, 2310008J16Rik antibody, 2810405N18Rik antibody, Antrx1 antibody, Tem8 antibody, anthrax toxin receptor 1 antibody, ANTXR1 antibody, Antxr1 antibody
- 背景
- The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8) (1). This protein, which exists in three isoforms (36, 40, and 60 kDa), is highly expressed in tumor vessels as well as in the vasculature of developing embryos, suggesting that it may normally play a role in angiogenesis. However, it also acts as the receptor for anthrax toxin (2). Following the binding of this protein by the protective antigen (PA) of anthrax, PA is cleaved and heptamerizes to form the binding site for both edema factor (EF) and lethal factor (LF) (3). This complex is then endocytosed by the cell, acidification in endosomes allows the release of EF and LF into the cytoplasm where they interfere with MAPK signaling and induce apoptosis (4).Synonyms: ANTXR1, ATR, TEM8, Tumor endothelial marker 8
- 基因ID
- 84168
- NCBI登录号
- NP_444262
- UniProt
- Q9H6X2
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