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MYO5A 抗体 (Internal Region)

MYO5A 适用: 人, 小鼠, 大鼠, Cow WB, IF, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN499147
发货至: 中国
  • 抗原 See all MYO5A 抗体
    MYO5A (Myosin VA (MYO5A))
    抗原表位
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    人, 小鼠, 大鼠, Cow
    宿主
    • 21
    • 1
    山羊
    克隆类型
    • 22
    多克隆
    标记
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYO5A antibody is un-conjugated
    应用范围
    • 11
    • 10
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    序列
    C-ETKQLELDLN
    特异性
    This antibody is expected to recognize both reported isoforms (NP_000250.3 and NP_001135967.1).
    交叉反应 (详细)
    Species reactivity (expected):Rat, Bovine.
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide sequence from the internal region of the protein sequence according to NP_000250.3, NP_001135967.1. Genename: MYO5A
    Top Product
    Discover our top product MYO5A Primary Antibody
  • 应用备注
    Peptide ELISA: Limit Dilution: 1/8000. Western blot: 1-3 μg/mL. This antibody detects a band of approx. 200 kDa in lysates of cell lineJurkat.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MYO5A (Myosin VA (MYO5A))
    别名
    Myosin-Va (MYO5A 产品)
    别名
    myo5a antibody, MGC53270 antibody, si:dkey-266j9.1 antibody, MYOA antibody, MYO5A antibody, D antibody, Dop antibody, Myh12 antibody, 9630007J19Rik antibody, AI413174 antibody, AI661011 antibody, Dbv antibody, MVa antibody, Myo5 antibody, MyoVA antibody, Sev-1 antibody, d antibody, d-120J antibody, flail antibody, flr antibody, DILUTE antibody, myoxin) antibody, non-muscle antibody, GS1 antibody, MYH12 antibody, MYO5 antibody, MYR12 antibody, myosin VA L homeolog antibody, myosin VAa antibody, myosin VA antibody, myosin va antibody, myo5a.L antibody, myo5aa antibody, MYO5A antibody, PY04789 antibody, Myo5a antibody
    背景
    Myosin-Va has been implicated in the regulation of vesicle trafficking in neurons and melanocytes. It has been suggested that class V myosins associate with membrane vesicles through their C-terminal tails. Myosin V associates with synaptic vesicles and forms a stable complex with the synaptic vesicle membrane proteins, synaptobrevin II, and synaptophysin. The dilute Myo5a gene mutation in myosin Va leads to mental retardation, variable cellular immunodeficiency and impaired melanocyte function (pigmentary dilution), known as Griscelli syndrome in humans. Myosin Va regulates melanosome distribution along microfilaments. It is found in association with the centrosome at all stages of the cell cycle. In the interphase stage, myosin Va is found in pericentriolar material. During cell division, it is found in the cytoplasm and concentrates in a trail between migrating centrioles and in the mitotic spindle poles and spindle fibers.Synonyms: Dilute myosin heavy chain, MYH12, MYO5A, Myosin heavy chain 12, Myoxin, non-muscle
    分子量
    215kDa (NP_000250.3).
    基因ID
    4644
    NCBI登录号
    NP_000250
    UniProt
    Q9Y4I1
    途径
    Hormone Transport, Peptide Hormone Metabolism
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