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MAPK15 抗体

MAPK15 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498400
发货至: 中国
  • 抗原 See all MAPK15 抗体
    MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))
    适用
    • 48
    • 17
    • 3
    人, 小鼠
    宿主
    • 35
    • 13
    克隆类型
    • 37
    • 11
    多克隆
    标记
    • 25
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPK15 antibody is un-conjugated
    应用范围
    • 39
    • 31
    • 16
    • 13
    • 7
    • 7
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of ERK8 protein. (region surrounding Asp171)
    交叉反应 (详细)
    Species reactivity (tested):Human and Mouse.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product MAPK15 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    PBS, pH 7.2, 0,05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))
    别名
    MAPK15 (MAPK15 产品)
    别名
    MGC138052 antibody, MGC99048 antibody, erk7 antibody, zgc:110345 antibody, ERK7 antibody, ERK8 antibody, BC048082 antibody, Erk7 antibody, ATMPK15 antibody, F25P22.9 antibody, F25P22_9 antibody, MAP kinase 15 antibody, mitogen-activated protein kinase 15 antibody, mitogen-activated protein kinase 15 L homeolog antibody, MAP kinase 15 antibody, MAPK15 antibody, mapk15.L antibody, mapk15 antibody, Tsp_00300 antibody, Mapk15 antibody, MPK15 antibody
    背景
    The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.Synonyms: ERK8, Extracellular signal-regulated kinase 8, Mitogen-activated protein kinase 15
    分子量
    approx. 60 kDa
    基因ID
    225689
    NCBI登录号
    NP_620590
    UniProt
    Q8TD08
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