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FOSB 抗体

FOSB 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498127
发货至: 中国
  • 抗原 See all FOSB 抗体
    FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))
    适用
    • 66
    • 30
    • 14
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 60
    • 6
    克隆类型
    • 52
    • 14
    多克隆
    标记
    • 33
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FOSB antibody is un-conjugated
    应用范围
    • 46
    • 15
    • 15
    • 11
    • 11
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of FosB protein.
    交叉反应 (详细)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product FOSB Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000. Immunoflourescence: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))
    别名
    FOSB (FOSB 产品)
    别名
    FOSB antibody, zgc:92354 antibody, AP-1 antibody, G0S3 antibody, GOS3 antibody, GOSB antibody, fra-2 antibody, FBJ murine osteosarcoma viral oncogene homolog B antibody, FosB proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene B antibody, FOSB antibody, fosb antibody, Fosb antibody
    背景
    Fos and Jun dimerize to form Activator Protein-1 (AP-1), a transcriptional factor that binds to the 12-O-tetradecanoylphorbol 13-acetate (TPA) response element (TRE) of several cellular and viral genes including human collagenase, metallothionein II,a stromelysin, interleukin 2, SV40 and polyoma. Fos and Jun contain the 'leucine-zipper' motif that allows for dimerization and an adjacent basic domain required for biological activity. The functionally active form of Fos is in a heterodimer with a member of the Jun family. While Jun family members can form functional homodimers, studies indicate that Fos family members do not self-associate and therefore do not bind DNA on their own. The various dimers differ in their ability to transactivate AP-1 dependent genes.Synonyms: G0/G1 switch regulatory protein 3, G0S3, GOS3, GOSB, Protein fosB
    分子量
    approx. 35 kDa
    基因ID
    2354
    NCBI登录号
    NP_006723
    UniProt
    P53539
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