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GOPC 抗体 (Middle Region)

GOPC 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN497985
发货至: 中国
  • 抗原 See all GOPC 抗体
    GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
    抗原表位
    • 15
    • 11
    • 7
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    Middle Region
    适用
    • 82
    • 33
    • 10
    • 6
    • 6
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    • 3
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    • 1
    人, 小鼠
    宿主
    • 81
    • 1
    克隆类型
    • 73
    • 9
    多克隆
    标记
    • 29
    • 8
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    This GOPC antibody is un-conjugated
    应用范围
    • 44
    • 30
    • 30
    • 14
    • 14
    • 11
    • 8
    • 6
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    • 4
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Recognizes PIST (Intermediate Domain).
    交叉反应 (详细)
    Species reactivity (tested):Human and Mouse.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    17 amino acid peptide from near the center of Human PIST (Genbank accession No. AAG00572).
    亚型
    IgG
    Top Product
    Discover our top product GOPC Primary Antibody
  • 应用备注
    ELISA. Western Blot: PIST antibody can be used for the detection ob PIST at 1-2 μg/mL. Positive Control: PC-3 Cell Lysate. Immunohistochemistry on paraffin sections. Positive Control: Rat Colon Cell Lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
    别名
    GOPC / PIST (GOPC 产品)
    别名
    DKFZp459H2130 antibody, 2210402P09Rik antibody, AI844555 antibody, CAL antibody, FIG antibody, GOPC1 antibody, PIST antibody, fe38f01 antibody, wu:fe38f01 antibody, zgc:56254 antibody, zgc:65853 antibody, dJ94G16.2 antibody, cal antibody, gopc1 antibody, pist antibody, golgi associated PDZ and coiled-coil motif containing antibody, golgi-associated PDZ and coiled-coil motif containing antibody, golgi-associated PDZ and coiled-coil motif containing S homeolog antibody, GOPC antibody, Gopc antibody, gopc antibody, gopc.S antibody
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2) and is negatively regulated by TOR (Target of rapamycin) (3). PIST, a PDZ-containing protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6 (4-6). Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1. (6)Synonyms: CAL, CFTR-associated ligand, FIG, Fused in glioblastoma, Golgi-associated PDZ and coiled-coil motif-containing protein, PDZ protein interacting specifically with TC10
    基因ID
    57120
    NCBI登录号
    NP_001017408
    UniProt
    Q9HD26
    途径
    Maintenance of Protein Location, Asymmetric Protein Localization
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