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LAMP1 抗体

LAMP1 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN497981
发货至: 中国
  • 抗原 See all LAMP1 抗体
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 54
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    克隆类型
    • 80
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    多克隆
    标记
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    This LAMP1 antibody is un-conjugated
    应用范围
    • 85
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    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    Recognizes CD107a/LAMP1 (Center).
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    LAMP1 antibody was raised against a 15 amino acid peptide from near the center of Human LAMP-1.
    亚型
    IgG
    Top Product
    Discover our top product LAMP1 Primary Antibody
  • 应用备注
    ELISA. Western blot: CD107a/LAMP1 antibody can be used for the detection of CD107a/LAMP1 at1-2 μg/mL. Despite its predicted size, LAMP-1 migrates at 110 kDa in SDS-PAGE. Positive Control: EL4 Cell Lysate. Immunofluorescence. Positive Control: Human Colon Tissue Lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    别名
    CD107a / LAMP1 (LAMP1 产品)
    别名
    CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2) and is negatively regulated by TOR (Target of rapamycin) (3). A protein recently found to be involved in autophagy, LAMP-2, is a highly glycosylated protein associated with the lysosome (4,5). LAMP-1 shares much homology to LAMP-2 and is thought to have overlapping functions. Mice lacking LAMP-1 had very minor defects compared to those deficient in LAMP-2 expression (6). However, the loss of both proteins resulted in embryonic lethality (7), suggesting that each protein possesses some unique and necessary functions.Synonyms: CD107 Antigen-like Family Member A, LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1
    基因ID
    3916
    NCBI登录号
    NP_005552
    UniProt
    P11279
    途径
    Autophagy
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