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LAMP2 抗体 (C-Term)

LAMP2 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN497979
发货至: 中国
  • 抗原 See all LAMP2 抗体
    LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
    抗原表位
    • 16
    • 13
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    C-Term
    适用
    • 111
    • 71
    • 36
    • 16
    • 3
    • 3
    • 2
    • 1
    人, 小鼠
    宿主
    • 85
    • 41
    • 28
    克隆类型
    • 78
    • 75
    多克隆
    标记
    • 56
    • 20
    • 19
    • 14
    • 11
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LAMP2 antibody is un-conjugated
    应用范围
    • 113
    • 55
    • 49
    • 36
    • 31
    • 29
    • 25
    • 14
    • 13
    • 13
    • 11
    • 7
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    Recognizes CD107b/LAMP2 (C-term).
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    LAMP2 antibody was raised against a 17 amino acid peptide from near the carboxy of Human LAMP-2 (NP_054701).
    亚型
    IgG
    Top Product
    Discover our top product LAMP2 Primary Antibody
  • 应用备注
    ELISA. Western blot: Beclin-1 antibody can be used for the detection of Beclin-1 at 1-2 μg/mL. Despite its predicted size, LAMP-2 migrates at 115 kDa in SDS-PAGE. Positive Control: HepG2 Cell Lysate. Immunocytochemistry. Positive Control: HepG2 Cell Lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
    别名
    CD107b / LAMP2 (LAMP2 产品)
    别名
    CD107b antibody, LAMP-2 antibody, LAMPB antibody, LGP110 antibody, Lamp-2 antibody, Lamp-2a antibody, Lamp-2b antibody, Lamp-2c antibody, Mac3 antibody, cd107b antibody, lamp-2 antibody, lampb antibody, LAMP2 antibody, lamp2 antibody, DKFZp459J126 antibody, LGP-B antibody, sb:cb587 antibody, wu:fb14a06 antibody, zgc:103532 antibody, lysosomal associated membrane protein 2 antibody, lysosomal-associated membrane protein 2 antibody, lysosomal-associated membrane protein 2 S homeolog antibody, lysosomal membrane glycoprotein 2 antibody, LAMP2 antibody, Lamp2 antibody, lamp2.S antibody, lamp2 antibody
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2) and is negatively regulated by TOR (Target of rapamycin) (3). LAMP-2, a highly glycosylated protein associated with the lysosome (4), has recently been shown to be important in autophagy as mice deficient in this protein failed to convert autophagic vacuoles into vacuoles (5) leading to impaired degradation of long-lived proteins. This correlates with the finding that human LAMP-2 deficiency causing Danon's disease is associated with the accumulation of autophagic material in striated myocytes (6). LAMP-2 exists in multiple isoforms (7).Synonyms: LAMP-2, LAMP-2C, LAMPB, Lysosome-associated membrane glycoprotein 2
    基因ID
    3920
    NCBI登录号
    NP_054701
    UniProt
    P13473
    途径
    Autophagy
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