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Beclin 1 抗体 (C-Term)

BECN1 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN497977
发货至: 中国
  • 抗原 See all Beclin 1 (BECN1) 抗体
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    抗原表位
    • 16
    • 15
    • 14
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 197
    • 87
    • 72
    • 10
    • 9
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 166
    • 34
    • 2
    克隆类型
    • 165
    • 37
    多克隆
    标记
    • 91
    • 17
    • 15
    • 14
    • 13
    • 13
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Beclin 1 antibody is un-conjugated
    应用范围
    • 142
    • 94
    • 56
    • 34
    • 30
    • 27
    • 26
    • 22
    • 20
    • 13
    • 13
    • 4
    • 4
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    Recognizes Beclin-1 (C-term).
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Beclin-1 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of Human Beclin-1.
    亚型
    IgG
    Top Product
    Discover our top product BECN1 Primary Antibody
  • 应用备注
    ELISA. Western blot: Beclin-1 antibody can be used for the detection of Beclin-1 at 0.5-1 μg/mL. Positive Control: A431 Cell Lysate. Immunocytochemistry. Positive Control: A431 Cell Lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    别名
    Beclin-1 (BECN1 产品)
    别名
    beclin-1 antibody, atg6 antibody, vps30 antibody, beclin1 antibody, Beclin-1 antibody, becn1 antibody, zgc:73097 antibody, ATG6 antibody, VPS30 antibody, 4921513J16Rik antibody, 5430417M23Rik antibody, Atg6 antibody, beclin 1 antibody, beclin 1, autophagy related antibody, beclin 1 protein antibody, beclin-1 antibody, beclin family protein antibody, beclin 1, autophagy related L homeolog antibody, BECN1 antibody, becn1 antibody, atg6 antibody, CpipJ_CPIJ011087 antibody, PTRG_07825 antibody, SJAG_01876 antibody, Becn1 antibody, becn1.L antibody
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells (1,2). Beclin-1, a coiled-coil Bcl-2-interacting protein homologous to the yeast autophagy gene apg6 (3,4), is a mammalian autophagy gene that can inhibit tumorigenesis and is expressed at reduced levels in human breast carcinoma, suggesting that defects in autophagy proteins may contribute to the development or progression of tumors (5). Bcl-2 can bind to Beclin-1 and inhibit Beclin-1-dependent autophagy in yeast and mammalian cells, suggesting that Bcl-2 functions as an anti-autophagy protein as well as an anti-apoptotic protein, which helps maintain autophagy at levels that are more compatible with cell survival rather than cell death (6).Synonyms: BECN1, Coiled-coil myosin-like BCL2-interacting protein, GT197, Protein GT197
    基因ID
    8678
    NCBI登录号
    NP_003757
    UniProt
    Q14457
    途径
    Autophagy
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