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- 抗原 See all BRCA1 抗体
- BRCA1 (Breast Cancer 1 (BRCA1))
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抗原表位
- pSer988
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BRCA1 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF)
- 原理
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.
- 序列
- IKSpFV
- 特异性
- BRCA1 (phospho-Ser988) antibody detects endogenous levels of BRCA1 only when phosphorylated at serine 988.
- 交叉反应
- 人
- 产品特性
- Antibody Reactive Against Synthetic Peptide.
- 免疫原
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S988 of human BRCA1.
- Top Product
- Discover our top product BRCA1 Primary Antibody
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- 应用备注
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Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
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Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization." in: The Journal of biological chemistry, Vol. 278, Issue 3, pp. 2015-20, (2003) (PubMed).
: "The relationship between the roles of BRCA genes in DNA repair and cancer predisposition." in: Trends in molecular medicine, Vol. 8, Issue 12, pp. 571-6, (2002) (PubMed).
: "In search of the tumour-suppressor functions of BRCA1 and BRCA2." in: Nature, Vol. 408, Issue 6811, pp. 429-32, (2000) (PubMed).
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Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization." in: The Journal of biological chemistry, Vol. 278, Issue 3, pp. 2015-20, (2003) (PubMed).
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- 抗原
- BRCA1 (Breast Cancer 1 (BRCA1))
- 别名
- BRCA1 / RNF53 (BRCA1 产品)
- 别名
- BRCAI antibody, BRCC1 antibody, BROVCA1 antibody, IRIS antibody, PNCA4 antibody, PPP1R53 antibody, PSCP antibody, RNF53 antibody, iris antibody, pscp antibody, brcai antibody, brcc1 antibody, rnf53 antibody, brca1 antibody, BRCA1 antibody, LOC100224649 antibody, BRCA1, DNA repair associated antibody, breast cancer 1 antibody, breast cancer 1, early onset antibody, breast cancer 1 L homeolog antibody, BRCA1 antibody, brca1 antibody, LOC755086 antibody, Brca1 antibody, brca1.L antibody
- 基因ID
- 672
- 途径
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
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